Humoral and cellular immune responses are currently induced against hepatitis C virus (HCV) core following vaccination with core-encoding plasmids. However, the anti-core antibody response is frequently weak or transient. In this paper, we evaluated the effect of different additives and DNA-protein combinations on the anti-core antibody response. BALB/c mice were intramuscularly injected with a...

Using the NBD/Rh fluorescence assay the PEG 6000 induced phospholipid mixing of phosphatidylcholine liposomes containing cholesterol, diacylglycerol or phosphatidylethanolamine was measured. All 3 components shifted the PEG 6000 concentration necessary to induce 50% of maximal phospholipid mixing to lower concentrations. After the addition of PEG cholesterol containing PC liposomes exhibit diff...

The main aim of the present investigation was to develop in situ gelling mucoadhesive liquid suppositories of ondansetron by using mucoadhesive polymers such as sodium alginate, methyl cellulose and polyvinylpyrrolidone. Polyethylene glycol was used to modify gelation temperature. Mucoadhesive liquid suppositories of ondansetron were prepared by adding mucoadhesive polymers (0.8% w/w) to the fo...

Chilli is an important vegetable and spice crop in India. It cultivated under both irrigated rainfed conditions. Most of the local genotypes are grown conditions they known to withstand drought some extent with lowered yield. Since chilli varieties or hybrids not developed for tolerance, experiment was conducted evaluate 34 collected from different regions tolerance using polyethylene glycol 60...

Abstract: A comparative study for evaluating the influence of metal oxide nanoparticles (MONPs) (Al2O3, TiO2, and SiO2) on seed germination seedling growth in okra was implemented under water deficit stress stimulated by PEG-6000. The results revealed that additive SiO2 (SNPs) Al2O3 (ANPs) have significant positive effect seeds germination, while a reduction were observed using TiO2 (TNPs) at 5...

Large numbers of viable protoplasts of pea (Pisum sativum) and grass pea (Lathyrus sativus) were efficiently and reproducibly obtained and, for the first time, fused. Different procedures for fusion were compared, based either on electrofusion (750, 1000, 1250 or 1500 V cm(-1)), or on the use of macro or micromethods with a polyethylene glycol (PEG 6000 or PEG 1540), or a glycine/high pH soluti...

The adverse effects of salinity and PEG-induced water stress on growth of Matricaria chamomilla were assessed at the germination stage using osmotic solution of NaCl (0, -0.175, 0.358, -0.541, -0.716 MPa), and polyethylene glycol (PEG 6000) (0, -0.05, -0.1, -0.2, -0.3 MPa), respectively. Effect of NaCl salinity stress (0, 40, 80, 120 and 190 mM NaCl) at early growth stage of chamomile was also ...

Efavirenz is an HIV-1 specific, non-nucleoside reverse transcriptase inhibitor (NNRTI).It is an antiretroviral agent indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection, which is not soluble in water and lower absorption in gastric fluid. In order to improve the solubility and oral absorption of the drug in gastric fluid and to enhance its dissolution rate, soli...