Approximately 85% of patients with CF are pancreatic insufficient (PI), requiring enzyme replacement therapy (PERT) all fat-containing food & drinks. PERT is commenced based on clinical signs PI such as steatorrhea poor weight gain. Faecal elastase (FE) tests used to confirm PI. This audit was conducted see if adults at a UK centre have FE result, check usage genotype CFTR modulator treatment. ...

This investigation presents a heuristic method for consumable resource allocation problem in multi-class dynamic Project Evaluation and Review Technique (PERT) networks, where new projects from different classes (types) arrive to system according to independent Poisson processes with different arrival rates. Each activity of any project is operated at a devoted service station located in a n...

In this paper the expression for the mean in the PERT method is considered. This mean involves a parameter k, that sometimes has been set to 4. Insisting on the similarity between the beta and the normal distributions, certain hypotheses are proposed that lead to k necessarily being exactly 4. More speci6cally, by using the moments of the second and fourth orders, it is shown that the usual bet...

Perencanaan waktu yang baik sangat dibutuhkan dalam penjadwalan proyek agar dapat dipastikan bahwa perencanaan ditetapkan tercapai dengan kesalahan paling kecil namun hasil maksimal mendayagunakan apa ada. Sebab itu, periode menjadi salah satu hal penting selain biaya untuk menyelesaikan suatu proyek. Jaringan kerja atau Network Planning adalah cara manajemen serta pengendalian proyek, menyajia...

The process of "transitioning" to adulthood for youth with disabilities has long been recognized to be an important but understudied public policy concern. This paper evaluates the labor market effects of Virginia’s school-to-work vocational evaluation program, PERT. Using a unique panel data set containing more than a decade of employment and service provision, we provide the first-ever assess...

Exocrine pancreatic insufficiency (EPI), an important cause of maldigestion and malabsorption, results from primary pancreatic diseases or secondarily impaired exocrine pancreatic function. Besides cystic fibrosis and chronic pancreatitis, the most common etiologies of EPI, other causes of EPI include unresectable pancreatic cancer, metabolic diseases (diabetes); impaired hormonal stimulation o...

Pancreatic exocrine insufficiency (PEI) frequently occurs secondary to exocrine pancreatic disease (e.g. chronic pancreatitis, cystic fibrosis, cancer) or pancreatic/gastrointestinal surgery, resulting in the maldigestion of nutrients and consequently malnutrition. Pancreatic enzyme replacement therapy (PERT) is the cornerstone of PEI management. Despite its clinical relevance, the diagnosis of...