Postoperative nausea, retching and vomiting are among the most common postoperative complaints and key causes of morbidity after general, regional, or local anesthesia and surgery. To study the clinical effect of ondansetron on patients with gynecologic laparoscopic operation. We performed a comparative-analysis of published, randomized, controlled trials to determine the relative efficacy and ...

Postoperative nausea and vomiting (PONV) occur in 30-50% of patients undergoing general anesthesia and in 70-80% of high PONV risk patients. In this study, we investigated the efficacy of fosaprepitant, a neurokinin-1 (NK1) receptor antagonist, compared to ondansetron, a selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, in moderate to high PONV risk patients from our previous ra...