This study used data of in vitro fertilization (IVF) cycles from 3,221 patients during 2004 to 2013, collected in Leuven University Fertility Center, aiming to identify patient and cycle characteristics to predict pregnancy and live birth rate. Variables include age, gonadotrophin dose, year of the IVF cycle, implantation problems, transport problems, ovulation problems, male pathology, pituita...

Preterm births have been seen to psychological and financial implications; current surveys suggest that amongst the various methods of preterm prediction, there is yet exist a reliable standard means predicting births. This study investigates application electrohysterogram tocogram signals acquired at points during third pregnancy trimester, alongside information from patients' medical health r...

BACKGROUND Over-the-counter-medication (OTC-medication) use during pregnancy can be potentially harmful for the fetus. To successfully counsel the patient it is important to know if the patient is at risk. In this study possible predictors for OTC-medication use were identified and a model was designed to predict OTC-medication use during pregnancy. METHODS We performed a post-hoc analysis on...

BACKGROUND Preeclampsia and HELLP syndrome may have serious consequences for both mother and fetus. Women who have suffered from preeclampsia or the HELLP syndrome, have an increased risk of developing preeclampsia in a subsequent pregnancy. However, most women will develop no or only minor complications. In this study, we intend to determine cost-effectiveness of recurrence risk guided care ve...

Prediction of hypertensive disease in pregnancy remains challenging. Risk factor based screening utilizing history, physical characteristics, uterine artery Doppler and serum markers have been used with varying success. As hypertension in pregnancy appears to be associated with changes in the maternal vasculature, we have investigated the utility of maternal arterial elasticity measurement, pri...

Cumulus cell (CC) gene expression is being explored as an additional method to morphological scoring to choose the embryo with the highest chance to pregnancy. In 47 ICSI patients with single embryo transfer (SET), from which individual CC samples had been stored, 12 genes using QPCR were retrospectively analyzed. The CC samples were at the same occasion also used to validate a previously obtai...

Objective. To investigate the endocrine and/or clinical characteristics of women with low anti-Müllerian hormone (AMH) that could improve the accuracy of IVF outcome prediction based on the female age alone prior to the first GnRH antagonist IVF cycle. Methods. Medical records of 129 patients with low AMH level (<6.5 pmol/L) who underwent their first GnRH antagonist ovarian stimulation protocol...

abstract background: the incidence of pregnancy induced hypertension (pih) which is one of the three main causes of maternal-neonatal morbidity and mortality is 5-7%, and prediction of this disorder is very important in maternal and neonatal health. methods: the type of this study is analytical (comparative-prospective) and its purpose is to evaluate the isometric exercise test (let) and roll-o...

During pregnancy, elevated markers of coagulation and fibrinolytic system activation, such as D-Dimer, indicate increased thrombin activity and increased fibrinolysis following fibrin formation. Testing for D-Dimer during pregnancy could therefore be useful for the diagnosis and prediction of a venous thromboembolic event (VTE) or pregnancy-related complications, and for monitoring antithrombot...