introduction: dentin hypersensitivity is one of the most common complications that affect patients after periodontal therapy. recently low level laser therapy has been introduced as a new treatment modality and has produced beneficial results. the purpose of this study is to evaluate the effect of low level laser therapy toothbrushes in reduction of dentin hypersensitivity. methods: in this pil...

introduction: port wine stains (pws) are congenital vascular malformations. pulsed dye laser (pdl) is the treatment of choice till now, although many lesions do not respond completely. one of possible options is long pulsed alexandrite laser. some literatures confirmed its efficacy. the aim of the present study is to determine the efficacy of this laser as an option in treating refractory pws i...

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Hypersensitivity to anticonvulsant drugs have been reported many times. But anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal drug reaction with cutaneous and systemic reaction to the arene oxide-producing anticonvulsants, phenytoin, carbamazepine, and Phenobarbital sodium. The hall-mark features of this syndrome are: Fever, rash and lymphadenopathy. The epoxide hydrolase en...

The aim of this study was to evaluate changes that occur in motility parameters of progesterone treated mouse spermatozoa during course of hyperactivation. Mouse spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min of incubation. For each sperm, one second of movement of the head-midpiece junction was traced from the videotape and for each tracing sev...

background : this study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters. receptors for estrogen and progesterone are predictive and prognostic markers of endometrial and breast cancers. however, their clinical significance in epithelial ovarian cancer is not c...

oxaliplatin, a third generation of platinum-based anti-neoplastic agent has been approved for colorectal cancer in both adjuvant and metastatic settings. in addition, oxaliplatin is also indicated for other gastrointestinal malignancies such as metastatic pancreatic cancer in combination with gemcitabine. its common toxicities include infusional hypersensitivity reaction (hsr), gi symptoms with...

Hypersensitivity reactions can be a side effect to any vaccine, but they are usually rare. The COVID-19 vaccination may cause hypersensitivity, and several cases of delayed hypersensitivity (DH) hyaluronic acid (HA) dermal filler have been documented. current report presents case 36-year-old female patient with DH HA after receiving the Pfizer-BioNTech vaccine. Symptoms, including dryness, swel...

Objective Objective: Gelatinases degrade extracellular matrix (ECM) components to make physiological remodeling and contribute to pathological tissue destruction in endometriosis. It is known that gelatinases’ function is resistant to suppression by progesterone in endometriosis. The ability of progesterone to impact gene expression depends on the progesterone receptor-A/-B (PR-A/PR-B) ratio. A...

Background: To compare the effect of GnRH agonist administration with vaginal progesterone on serum progesterone in Luteal phase in control ovarian hyper stimulation and intrauterine insemination cycles Materials and Methods: In this clinical trial, 242 infertile patients because of UEI (unexplained inferetility candidate for ovarian stimulation and intrauterine insemination reffering to infert...