Introduction: Patients with schizophrenia characteristically exhibit cognitive deficits. The level of cognitive impairment is found to predict the functional outcome of the illness more strongly than the severity of positive or negative symptoms. The purpose of this study was to assess the efficacy of ondansetron, a 5-HT3 receptor antagonist as an adjuvant agent in the treatment of chronic...

A robust inconsistent handed advantage exists for episodic retrospective memory processes. The current study was undertaken to test whether this handedness difference extends to the domain of prospective memory (PM). Two studies, one based on a self-report measure (the Prospective and Retrospective Memory Questionnaire) and the second involving a performance-based test (Memory for Intentions Sc...

OBJECTIVE To study prospective and retrospective memory in patients with mild Alzheimer's disease (AD). METHOD Twenty mild AD and 20 matched normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, using CDR 1 and MMSE scores from 16 to 24 for mild AD. All subjects underwent retrospective (Rey Auditory Verbal Learning Test, RAVLT) and prospective m...

a r t i c l e i n f o The current study investigates whether individual differences in retrospective memory and executive flexibility tasks mediate the relation between age and performance on laboratory and naturalistic prospective memory tasks. One hundred and ninety-seven people aged 61 to 95 years performed four laboratory prospective memory tasks, two naturalistic prospective memory tasks, ...

Increasing studies suggest the importance of including prospective memory measures in clinical evaluation of dementia due to its sensitivity and functional relevance. The Prospective and Retrospective Memory Questionnaire (PRQM) is originally a self-rated memory inventory that offers a direct comparison between prospective and episodic memory. However, the informant's report has been recognized...

Are self-report measures of prospective memory (ProM) reliable and valid? To examine this question, 240 undergraduate student volunteers completed several widely used self-report measures of ProM including the Prospective Memory Questionnaire (PMQ), the Prospective and Retrospective Memory Questionnaire (PRMQ), the Comprehensive Assessment of Prospective Memory (CAPM) questionnaire, self-report...

Previous work has hinted that prospective and retrospective coding modes exist in hippocampus. Prospective coding is believed to reflect memory retrieval processes, whereas retrospective coding is thought to be important for memory encoding. Here, we show in rats that separate prospective and retrospective modes exist in hippocampal subfield CA1 and that slow and fast gamma rhythms differential...

BACKGROUND There is some evidence that patients with Parkinson's disease may impaired in prospective memory performance (planning and self initiated realisation of delayed intentions). Little is known about the effect of the disease on distinct phases of prospective memory and the potential mechanisms underlying these effects. OBJECTIVE To investigate intention formation, intention retention,...