Insecticide-treated nets and indoor residual spray programs for malaria control are entirely dependent on pyrethroid insecticides. The ubiquitous exposure of Anopheles mosquitoes to this chemistry has selected for resistance in a number of populations. This threatens the sustainability of our most effective interventions but no operationally practicable way of resolving the problem currently ex...

Allethrin, present in mosquito coil is a pyrethroid pesticide. Pyrethroids are used as insecticides worldwide. Self poisoning with mosquito coil is very rare. We describe a case of attempted suicide by consumption of mosquito coil. Patient recovered without any sequel.

A simple method for the synthesis of octahydroquinazolinone derivatives in the presence of BF3.SiO2 and Insecticide activity of these compounds against spodoptera litura was investigated to be comparable to commercial pyrethroid insecticides, Cypermethrin and Cyhalothrin. The structure of the isolated compounds was characterized by 1HNMR and FT-IR spectroscopy.The proposed method had some ad...

Aedes aegypti is the primary vector of various relevant arthropod-borne viral infectious diseases worldwide. The mosquito control is still mainly performed by using insecticides but their effectiveness is increasingly questioned nowadays. We here conducted a study on Ae. aegypti resistance development towards several commonly used insecticides in the capital city of Jakarta, Indonesia. In order...

The voltage-sensitive sodium (Na+) channel (Vssc) is the target site of pyrethroid insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or multiple amino acid substitution(s) in this channel. In Southeast Asia, two major Vssc types confer pyrethroid resistance in the dengue mosquito vector Aedes aegypti, namely, S989P+V1016G and F1534C. We expressed s...

The prevention of Chagas disease is based primarily on the chemical control of Triatoma infestans (Klug) using pyrethroid insecticides. However, high resistance levels, correlated with control failures, have been detected in Argentina and Bolivia. A previous study at our laboratory found that imidacloprid could serve as an alternative to pyrethroid insecticides. We studied the delayed toxicity ...

A total of 53 strains of onion thrips, Thrips tabaci Lindeman, were established, of which 14 strains were collected from persimmon fruit and 39 strains from a vetch weed, Vicia angustifolia, in commercial persimmon orchards in Wakayama Prefecture. Susceptibility to insecticides was evaluated by the Petri dish-spraying tower method. Pyrethroid-resistant strains and pyrethroid-susceptible strains...

BACKGROUND Chagas' disease is an important public health concern in Latin America. Despite intensive vector control efforts using pyrethroid insecticides, the elimination of Triatoma infestans has failed in the Gran Chaco, an ecoregion that extends over Argentina, Paraguay, Bolivia and Brazil. The voltage-gated sodium channel is the target site of pyrethroid insecticides. Point mutations in dom...