The reduction of mortality in patients with sepsis depends on the early identification and treatment at-risk patients. aim was to evaluate HLA-DR expression surface monocytes (MHLA-DR ratio), index (CD64 neutrophils/MHLA-DR C-reactive protein (CRP) development sepsis. We prospectively enrolled 77 critically ill patients, 59 stroke 18 traumatic brain injuries. biomarkers were tested at baseline ...

background and objective: brucellosis is a main transmittable zoonotic disease, which is endemic, and a common health burden in iran. adenosine deaminase (ada) is an essential enzyme which is involved in purine metabolism and its role in immune system is very important. the aim of this study was to determine serum changes of ada and c-reactive protein (crp) levels in patients with brucellosis. ...

conclusions crp, a well-known acute phase reactant that increases rapidly in various inflammatory processes, can be accepted as a strong predictor in classifying different grades of the disease, and treatment can be reliably planned according to this classification. results mean crp levels of groups were found to be significantly different, 18.96 mg/l in group i, 133.51 mg/l in group ii, and 23...

conclusions considering that no significant difference was found in the proven vitamin a side effects, due to the increase in crp, frequent clinical and biochemical controls are required along with vitamin a supplementation. patients and methods this study was a double blind randomized clinical trial. in the main study, vitamin a (as retinyl palmitate) was given to 35 multiple sclerosis (ms) pa...

BACKGROUND & OBJECTIVES We evaluated pro- and anti-oxidant disturbances in sepsis and non-sepsis burn patients with systemic inflammatory response syndrome (SIRS). Adhesion molecules and inflammation markers on leukocytes were also analyzed. We hypothesized that oxidative stress and leukocyte activation markers can lead to the severity of sepsis. METHODS In 28 severe sepsis and 27 acute burn ...

neonatal sepsis is a disease of infants who are less than 1 month of age. these infants are clinically ill, and their blood culture are positive for bacteria. the reported incidence of neonatal sepsis for allinfants is 1 to 10 per 1000 live births. the mortality rate is 4.2-26%. the clinical signs are not specific and diagnosis of neonatal sepsis is one of the most difficult tasks in clinical m...

To explore the favourable functions of polysaccharide from Spirulina platensis (PSP) on sepsis-originated acute lung injury, together with corresponding mechanisms. 60 male SD rats were randomly separated into sham, sepsis, and sepsis+PSP group 20 in each group. Sepsis rat model was constructed by cecal ligation puncture (CLP). The mortality sepsis-related symptoms used to judge success. CLP su...

Aim: To assess the diagnostic accuracy of complete blood count with band versus total neutrophil ratio and C-reactive proteins as an efficient analytical procedure for determining early onset sepsis in neonates. Study design: Cross sectional study Place duration study: Department Paediatric Medicine, Abbas Institute Medical Sciences Muzafarabad, AJ Kashmir from 01-02-2022 to 31-07-2022. Methodo...