Major pathological response after neoadjuvant cisplatin-based chemotherapy for early-stage NSCLC has been shown to predict survival. This not demonstrated immune checkpoint inhibitors. In IONESCO multicenter phase II trial, 3 cycles of durvalumab were administered in stage IB>4cm–IIIA, non N2 resectable (TNM 8th edition) before surgery. We report here the updated analysis on disease-free surviv...

Ischemia and reperfusion injury of the skeletal muscle is a common and serious condition observed in patients admitting to peripheral vascular surgery, interventional radiology and cardiology departments. Resveratrol (RVT) being a strong natural antioxidant is found in deal of red wine and Mediterranean diet. In the present study, male Spraque-Dawley rats were randomized into two groups of equa...

Methods of site response analysis require theoretical and empirical testing and validation before they can be used in seismic hazard assessment. Comparison of site amplification function (SAF) calculated using earthquake data recorded by seismic arrays with SAF obtained using analytical approaches represent the most important tests of reliability of those methods. The Treasure Island (TI) downh...

frying oils showed an increase in peroxide value (pv) at the initial stages of the frying process followed by a decrease, and there was no correlation between pv and total polar compounds (tpc) in the same set of frying oils. all the frying oils had pvs lower than 4.42 meq o2 kg-1 oil during the frying process and, consequently, none of them was above the limit of 10 meq o2 kg-1 oil for edible ...

This paper considers certain aspects of the analysis of moiety-conserved cycles in terms of metabolic control analysis. Two response coefficients are discussed: the response coefficient with respect to the total number of moles in a cycle (RVT), and the response coefficient with respect to perturbations to the internal state of a pathway (RVS). The relationship between these two different measu...

At 34 weeks gestation she went into premature labour and both twins were delivered vaginally. The first twin (male) was cephalic presentation and born with Apgar scores of 5 and 8 at 1 minute and 5 minutes respectively and weighed 2.54 kg. The second twin (female), also cephalic presentation diagnosed as an intrauterine death (IUD) and a macerated stillborn weighing 1.94 kg was delivered. Two s...

OBJECTIVE The aim of this study is to assess our results of treatment of women with stage I cervical cancer>2 cm in diameter seeking fertility preservation. Treatment consisted of Laparoscopic Pelvic and Paraaortic Lymphadenectomy (LPPLND), and when no nodal metastasis was detected, neoadjuvant chemotherapy (NACT) followed by radical vaginal trachelectomy (RVT). Patients with positive lymph nod...