نتایج جستجو برای: replication slippage

تعداد نتایج: 104069  

There have been many researches on object grasping in cooperating systems assuming no object slippage and stable grasp and the control system is designed to keep the contact force inside the friction cone to prevent the slippage. However undesired slippage can occur due to environmental conditions and many other reasons. In this research, dynamic analysis and control synthesis of a cooperating ...

Journal: :international journal of robotics 0
farid sheikholeslam isfahan university of technology shahram hadian jazi shahrekord university mehdi keshmiri isfahan university of technology

there have been many researches on object grasping in cooperating systems assuming no object slippage and stable grasp and the control system is designed to keep the contact force inside the friction cone to prevent the slippage. however undesired slippage can occur due to environmental conditions and many other reasons. in this research, dynamic analysis and control synthesis of a cooperating ...

Journal: :The Journal of pathology 2008
T Graham S Halford K M Page I P M Tomlinson

Many cancers show a low level of microsatellite slippage and are labelled MSI-L (microsatellite instability--low). However, it is unclear whether this slippage can be attributed to some underlying genetic change that results in a mutator phenotype, analogous to mismatch repair deficiency in MSI-H cancers, or whether the apparent instability is the result of relatively frequent normal somatic sl...

Journal: :The Annals of Mathematical Statistics 1960

2010
Yogeshwar D. Kelkar Noelle Strubczewski Suzanne E. Hile Francesca Chiaromonte Kristin A. Eckert Kateryna D. Makova

Microsatellites are abundant in eukaryotic genomes and have high rates of strand slippage-induced repeat number alterations. They are popular genetic markers, and their mutations are associated with numerous neurological diseases. However, the minimal number of repeats required to constitute a microsatellite has been debated, and a definition of a microsatellite that considers its mutational be...

Journal: :Genome research 2012
Arunkanth Ankala Jordan N Kohn Anisha Hegde Arjun Meka Chin Lip Hon Ephrem Syed H Askree Shruti Bhide Madhuri R Hegde

Non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), and microhomology-mediated replication-dependent recombination (MMRDR) have all been put forward as mechanisms to explain DNA rearrangements associated with genomic disorders. However, many nonrecurrent rearrangements in humans remain unexplained. To further investigate the mutation mechanisms of these copy number v...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Christophe Penno Virag Sharma Arthur Coakley Mary O'Connell Motherway Douwe van Sinderen Lucyna Lubkowska Maria L Kireeva Mikhail Kashlev Pavel V Baranov John F Atkins

Escherichia coli and yeast DNA-dependent RNA polymerases are shown to mediate efficient nascent transcript stem loop formation-dependent RNA-DNA hybrid realignment. The realignment was discovered on the heteropolymeric sequence T5C5 and yields transcripts lacking a C residue within a corresponding U5C4. The sequence studied is derived from a Roseiflexus insertion sequence (IS) element where the...

Adhesion level for the proper running of rail wheelset on track has remained a significant problem for researchers in detecting slippage to avoid accidents. In this paper, the slippage of rail wheels has been observed applying forward and lateral motions to slip velocity and torsion motion. The longitudinal and lateral forces behavior is watched with respect to traction force to note correlatio...

Journal: :The International Journal of Arts Theory and History 2014

Journal: :Nucleic acids research 1990
J M Hancock G A Dover

The distribution patterns of shared short repetitive motifs in the expansion segments of the large subunit rRNA genes of different species show that these segments are coevolving as a set and that in two examined vertebrate species the RNA secondary structures are conserved as a consequence of runs of motifs in one region being compensated by complementary motifs in another. These unusual proce...

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