The aim of this study is to explore the differentially expressed lncRNAs, which may have potential biological function and diagnostic value in colorectal cancer (CRC). Through integrated data mining, we finally identified nine differentially expressed lncRNAs and their potential mRNA targets. After a series of bioinformatics analyses, we screened significant pathways and GO terms that are relat...

Guillain-Barré syndrome (GBS) is an acute autoimmune-mediated inflammatory demyelinating disease that causes rapidly progressing paralysis and occasionally respiratory failure. We hypothesized that interleukin (IL)-17 and IL-22 are elevated in GBS and participate in the autoimmune inflammatory response of GBS. We used sandwich enzyme-linked immunosorbent assay (ELISA) to measure the IL-17 and I...

In this paper, we propose a novel framework to analyze the theoretical properties of thelearning process for a representative type of domain adaptation, which combines data frommultiple sources and one target (or briefly called representative domain adaptation). Inparticular, we use the integral probability metric to measure the difference between the dis-tributions of two d...

Deoxyribonucleic acid (DNA) typing is widely used for personal identification. The allele frequency distribution of two STR loci (CSF1PO and TPOX) was studied in Egyptian population. A sample of 100 unrelated individuals inhabiting Dakahlia governorate (in Delta region) in Egypt was chosen randomly. Blood samples were collected after obtaining an informed consent. The DNA was extracted by using...

A series of novel 4-thioquinazoline derivatives containing chalcone moiety were designed, synthesized and systematically evaluated for their antiviral activity against TMV. The bioassay results showed that most of these compounds exhibited moderate to good anti-TMV activity. In particular, compounds M2 and M6 possessed appreciable protection activities against TMV in vivo, with 50% effective co...

OBJECTIVE To explore the clinicopathological features, surgical treatment techniques, and prognostic risk factors of intrahepatic cholangiocarcinoma (ICC). METHODS A total of 104 ICC cases were collected from January 2008 to December 2013 at Tianjin Medical University Cancer Institute and Hospital and divided into the hepatic hilum lymphadenectomy (HLL, 21 cases), extended hepatic hilum lymph...

Two antibiotics isolated from a culture MA-2465 were identified as aureothin and labilomycin, the chemical structures of which had been reported previously. It was also concluded that mycolutein and pulvomycin isolated as antibiotics in 1955 and 1957 respectively are also identical with aureothin and labilomycin. A cursory study of MA-2465 indicates that it is distinctly different from the cult...

The effect of solidification behavior on the microstructures and mechanical properties of Ni-Cr-Fe superalloy investment casting is given. Metallographic and image analysis have been used to quantitatively examine the microstructures' evolution. For the parts with the thickness of 3 mm and 24 mm, the volume fraction and maximum equivalent radius of the Laves phase increases from 0.3% to 1.2%, f...