The protective effect of flavonoids extracted from Scutellaria baicalensis Georgi on cerebral ischemia injury has been explored in experimental animals. Scutellaria flavonoid (SF) could significantly prolong gasping time (prolonged ratio, 23.79%) and survival time after carotid artery occlusion, and decrease attenuate malondialdehyde (MDA) content in damaged brain tissues from 118.56+/-47.95 nm...

Background Botanical supplements with flavonoids possess the ability to reduce inflammatory markers such as CRP, IL-6, and TNF-a. Also, they could potentially help reduce sugarinduced weight gain and facilitate weight loss. Diafin is a non-stimulant, botanical, weight loss product created from a blend of standardized Free-B-ring flavonoids and flavans from two plant extracts isolated from the S...

Scutellaria is widely used in traditional medicine as a medical plant, in Asian countries, especially in China. It has been applied in treatment because of its sedative, antithrombotic, anti-inflammatory, antioxidant, and antiviral effects. Scutellaria condensata Rech. f. subsp. pycnotricha (Rech. f.) Rech. f. is a wild perennial plant which  grows in Iran. In this study, GC-FID and GC-MS were ...

Production of baicalein, baicalin and wogonin by liquid culture of Scutellaria baicalensis cells derived from the plant root was studied. The maximum production obtained were 119 mg/L of baicalein at two week, 1372 mg/L of baicalin at eight week, and 14 mg/L of wogonin at two week. In addition, the production of baicalin was drastically increased to 1000 mg/L level at 3-week culture, and the ex...

Four new neo-clerodane diterpenoid alkaloids, named scutebarbatines I-L (1-4), were isolated from the whole plant of Scutellaria barbata D. DON. Their structures were established on the basis of detailed spectral analyses. In vitro, the four new compounds showed significant cytotoxic activities against three human cancer lines (HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 color...

The genus Scutellaria L., Lamiaceae family, Scutellarioideae sub-family is known as the most important medicinal plant in world. This research aimed to investigate flavonoid content of seven species from center, southwest, and west Iran. Via thin layer column chromatography, was extracted leaves then purified. To screen compositions, a chromatographic method applied by liquid chromatography mas...