The drug molecule Propranolol has been encapsulated by a sol-gel process in an organic-inorganic hybrid matrix by in-situ self-assembly; the 2D HETCOR solid state NMR spectroscopy provides direct proof of the intimate spatial relationship between the host matrix and guest drug molecules.

We report the genome sequence of Clostridium sp. strain DL-VIII, a novel Gram-positive, endospore-forming, solventogenic bacterium isolated from activated anaerobic sludge of a wastewater treatment plant. Aside from a complete sol operon, the 6,477,357-bp genome of DL-VIII reveals genes for several unique enzymes with applications in lignocellulose degradation, including two phenolic acid decar...

Research into supported palladium complexes is described. The complexes are immobilised on porous silica supports using both grafting and templated sol-gel techniques. The resultant complexes are efficient catalysts for various C-C bond forming reactions, including Heck, Suzuki and allylic substitution. The catalysts are stable and can be easily recovered and reused, making them suitable for cl...

This paper reports on a rapid new method for in-situ sol-gel deposition of silica layers in PDMS microchannels. A two-step process is used; first allowing TEOS to diffuse briefly into the channel, followed by acid catalysed hydrolysis and condensation. The silica coating results in an increased and stabilised electroosmotic flow. With this novel method there is no need for pretreatment of the m...

Topical administration of a drug in the conjunctival cul-de-sac is the treatment of choice for diseases of the anterior segment of eye. Development of ophthalmic drug delivery systems has always been challenging because of the drawbacks with this route, like non-productive absorption, drainage, induced lacrimation, tear turn over, impermeability of drugs to cornea. New approaches have been inve...

With the development of chemical synthetic strategies and available building blocks, in situ‐forming hydrogels have attracted significant attention in the biomedical fields over the past decade. Due to their distinct properties of easy management and minimal invasiveness via simple aqueous injections at target sites, in situ‐forming hydrogels have found a broad spectrum of biomedical applicatio...

Stable TiO2 sols were prepared using two nonaqueous sol–gel processes with titanium n-butoxide and titanium isopropoxide, respectively. Crystallization and phase transitions of powders and thin films were studied by ex situ and in situ X-ray diffraction. For both methods, TiO2 began to crystallize around 320 C in air. Using helium instead of air during heat treatment slowed down the crystalliza...