نتایج جستجو برای: smooth muscle cell

تعداد نتایج: 2007746  

2014
Feng Shi Xiaochun Long Allison Hendershot Joseph M. Miano Jane Sottile

Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular occlusive diseases. Phenotypically modulated smooth muscle cells exhibit increased proliferative and migratory properties that accompany the downregul...

Although the etiology of varicose veins remains unknown, recent studies have focused on endothelial cell integrity and function because the endothelium regulates vessel tone and synthesizes many pro- and anti-inflammatory factors. The aim of this study was to investigate the evidence involving the endothelium in the development of varicose vein disease. In addition, tissue remodeling was invest...

Journal: :Pulmonary Pharmacology & Therapeutics 2009

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2012

Journal: :Journal of atherosclerosis and thrombosis 1994
T Inaba N Yamada T Gotoda Y Saito S Yoshida Y Yazaki

In the present study, we demonstrated gene transcription of c-fms in smooth muscle cells isolated from an experimental rabbit model of arteriosclerosis (intimal smooth muscle cells), although there was no gene transcription of c-fms detected in medial smooth muscle cells. On immunocytochemical analysis, both types of smooth muscle cells similarly reacted with an antibody specific to muscle cell...

Journal: :Journal of Clinical Investigation 1999

Journal: :Circulation: Cardiovascular Interventions 2011

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