background: naltrexone, an opioid receptor antagonist shifts the immune response toward a th1 profile. in the current study, we evaluated the efficacy of the mixture of ntx and alum, as a new adjuvant, to enhance immune response and induce protection against leishmania major in a mouse model. methods : balb/c mice were immunized three times either autoclaved l. major promastigotes’ antigens alo...

in this study, we investigate the immunostimulatory effects of alcoholic extract of the coffee seed on cell-mediated immune response andcyclophosphamide-induced (cp) immunosuppressed mice. the assessment of cellular immune function was carried out by the measurement of delayed-type hypersensitivity (dth) response. according to the literature survey, cyclophosphamide has only suppressing effect ...

The recent findings that prolonged expression of certain adenovirus (Ad) vector-encoded proteins, including human alpha1-antitrypsin (huAAT), mouse erythropoietin (EPO), and human factor IX, can be achieved in animals that do not mount an immune response to the reporter protein were obtained with mouse strains which have been shown to be capable of mounting a cellular immune response against Ad...