specific and non- specific cellular immune responses were studied in 20 amoebiasis cases and 10 controls. all the study cases and controls were indians living in varanasi, india. ten amoebic liver abscess cases were patients admitted to university hospital. ten non-invasive intestinal amoebiasis cases constituted the second study group. non-specific immune responses were studied using e-rosette...

the prevalence of hepatitis c virus (hcv) is approximately 3% around the world. this virus causes chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. the effectiveness of interferon-α and ribavirin therapy is about 50% and is associated with significant toxicity and cost. hence, generating new vaccines or drugs is an obligation. however, there is no vaccine available for clinical u...

This study was conducted to investigate the effects of Curcuma zedoaria and Zingiber zerumbet on non-specific immune responses of grouper (Epinephelus coioides). Fish were fed an experimental diet containing 0, 0.5, 1.0, 2.5 g/kg of C. zedoaria and Z. zerumbet mixed diets twice daily for two weeks. Non-specific immune parameters such as respiratory burst activity, reactive oxygen species, phago...

objective: several vaccines against hiv have been investigated but none has been approved as an effective hiv vaccine. an approach that could induce stronger immune response against the pathogen is utilizing a multi-epitopic vaccine. this strategy was used in the design of several vaccines and resulted in improved immune responses. materials and methods: in this study a multi-epitopic fusion p...

This study was conducted to investigate the effects of Curcuma zedoaria and Zingiber zerumbet on non-specific immune responses of grouper (Epinephelus coioides). Fish were fed an experimental diet containing 0, 0.5, 1.0, 2.5 g/kg of C. zedoaria and Z. zerumbet mixed diets twice daily for two weeks. Non-specific immune parameters such as respiratory burst activity, reactive oxygen species, phago...

this study was conducted to investigate the effects of curcuma zedoaria and zingiber zerumbet on non-specific immune responses of grouper (epinephelus coioides). fish were fed an experimental diet containing 0, 0.5, 1.0, 2.5 g/kg of c. zedoaria and z. zerumbet mixed diets twice daily for two weeks. non-specific immune parameters such as respiratory burst activity, reactive oxygen species, phago...

Backgrounds: Most of the hepatitis C virus (HCV) infections elicit poor immune responses and 75% to 85% of cases become chronic therefore, the development of an effective vaccine against HCV is of paramount importance. In this study, we aimed to evaluate co-administration of HCV non-Structural Protein 2 and IL-12 DNA vaccines in C57BL/6 mice. Methods: A plasmid encoding full-length HCV NS2 prot...

conclusions this study suggests that the il-7 level of chb patients may be related to tfh cells. in chb patients, il-7 possibly increases the level of tfh cells and hbv-specific cellular immune responses and thereby reduces the hbv dna level. background in patients with chronic hepatitis b (chb), the relation of interkeukin-7 (il-7) to either the t follicular helper cells (tfh cells) or to a sp...

conclusions our results demonstrated that r-fla-a could induce cellular and humoral immune response as proper stimulant of poly-isotypic humoral responses. results immunized mice with adjuvanted flagellin showed a considerably increased lymphocyte proliferation compared with the control group (p = 0.004). high level of il-4 and ifn-γ secretion was observed in immunized mice compared with the co...

immune infertility, in terms of reproductive failure, has become a serious health issue involving approximately 1 out of 5 couples at reproductive age. semen that is defined as a complex fluid containing sperm, cellular vesicles and other cells and components, could sensitize the female genital tract. the immune rejection of male semen in the female reproductive tract is explained as the failur...