Premature ventricular complexes (PVCs), the first initiating beats of a variety of cardiac arrhythmias, have been associated with spontaneous calcium release (SCR) events at the cell level. However, the mechanisms underlying the degeneration of such PVCs into arrhythmias are not fully understood. The objective of this study was to investigate the conditions under which SCR-mediated PVCs can lea...

The jatrophane diterpene Pl-3, isolated in 2003 from Euphorbia platyphyllos, is a structurally complex natural product with highly promising biological properties that include pronounced antiproliferative activity and the inhibition of the efflux-pump activity of multidrug resistance p-glycoprotein. Herein, the synthesis of the eastern fragment of Pl-3 is outlined. The target compound is synthe...

We examined (structurally advantaged) non-Aborigines' willingness for political action against government redress to (structurally disadvantaged) Aborigines in Australia. We found non-Aborigines opposed to government redress to be high in symbolic racism and to perceive their ingroup as deprived relative to Aborigines. However, only perceived relative deprivation was associated with feelings of...

Abstract This article investigates the relationship between art and technology, pointing constants of a process cultural digestion which is mediated by very sovereign technological environment – Internet. Relying on multiplicity hybridization content formats, also user involved interactivity as constructive vector-relationships, new media internet are natural consequences artistic practices cre...

In the Kretschmann configuration, the bulk metal is in the form of a thin film of uniform thickness, bounded on one side by a high–refractive–index dielectric material and on the other side by a low–refractive–index dielectric material. A plane wave is launched in the optically denser dielectric material towards the metal film, in order to excite a surface–plasmon wave at the interface of the m...

Clearance by the retinal pigment epithelium (RPE) of shed photoreceptor outer segments (OSs), a tissue with one of the highest turnover rates in the body, is critical to the maintenance and normal function of the retina. We hypothesized that there is a potential role for photo-oxidation in OS uptake by RPE via scavenger receptor-mediated recognition of structurally defined lipid peroxidation pr...