We present SWAN, a statistical framework for robust detection of genomic structural variants in next-generation sequencing data and an analysis of mid-range size insertion and deletions (<10 Kb) for whole genome analysis and DNA mixtures. To identify these mid-range size events, SWAN collectively uses information from read-pair, read-depth and one end mapped reads through statistical likelihood...

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1. Bentham J, Rodriguez-Arnao J, Ross RJM. Acquired growth hormone resistance in patients with hypercatabolism. Harm Res. 1993;40:87-91. 2. Ross RJM, Chew SL. Acquired growth hormone resistance. Eur J Endocrinol. 1995;132:655-660. 3. Anker SD, Chua TP, Swan JW, Ponikowski P, Harrington D, Kox WJ, Poole-Wilson PA, Coats AJS. Hormonal changes and catabolic/anabolic imbalance in chronic heart fail...

The demand for sustainable agricultural production systems is increasing, and using growth-promoting microorganisms in plants has stood out because it decreases or even replaces chemical fertilizer use, reducing costs. This study aimed to evaluate the response of some applied seedlings primary orchids cultivated Brazil (Phalaenopsis sp. 'Taisuco Swan', Cymbidium atropurpureum, Dendrobium secund...

Expression of the transcription factor genes brachyury, Tbx2/3 and sall is characterized in detail for the first time in an indirectly developing spiralian with a feeding trochophore. In Hydroides elegans, gut formation proceeds by invagination during embryogenesis and is followed by feeding-dependent posterior growth during larval stages. Posterior growth gives rise to the reproductive and seg...

INTRODUCTION Most behavior checklists for attention problems or attention deficit/hyperactivity disorder (ADHD) such as the Child Behavior Checklist (CBCL) have a narrow range of scores, focusing on the extent to which problems are present. It has been proposed that measuring attention on a continuum, from positive attention skills to attention problems, will add value to our understanding of A...

Indicator dilution technique is more widely used during cardiac catheterization for the diagnosis and rough estimate of the size of intracardiac shunts and valvular regurgitation (Korner and Shillingford, 1955; Fox and Wood, 1957; Swan and Wood, 1957; Woodward et al., 1957; Shillingford, 1958; Carter et al., 1959; Carleton et al., 1960; Jose et al., 1960). Evans blue dye (T-1824) has long been ...