there is a complicated relation between cold flat rolling parameters such as effective input parameters of cold rolling, output cold rolling force and exit thickness of strips. in many mathematical models, the effect of some cold rolling parameters has been ignored and the outputs have not a desirable accuracy. in the other hand, there is a special relation among input thickness of strips, the ...

In embryonic and adult lenses, a balance of cell proliferation, cell cycle exit, and differentiation is necessary to maintain physical function. The molecular mechanisms regulating the transition of proliferating lens epithelial cells to differentiated primary lens fiber cells are poorly characterized. To investigate this question, we used gain- and loss-of-function analyses to modulate fibrobl...

Mesenchymal stem cells (MSCs) have the ability to differentiate into neuronal like cells under appropriate culture condition. In this study, we investigated whether MSCs derived from human peripheral blood (PB-MSCs) can differentiate into neuronal like cells by synergic effect of the growth factors EGF, bFGF and Noggin. For this purpose, the expression of five neuronal markers (Nestin, &beta II...

Cortical development is a complex process that involves many events including proliferation, cell cycle exit, and differentiation that need to be appropriately synchronized.. Neural stem cells (NSCs) isolated from embryonic cortex are characterized by their ability of self-renewal under continued maintenance of multipotency. The G1 phase of the cell cycle is mostly associated with cell cycle ar...

abstract among activities that can be used to prevent piping phenomena and reduce seepage and exit gradient are installation of cutoff wall and drain under hydraulic structures. hence in this study, to investigating the influence of each mentioned parameter on uplift force and exit gradient a computer model has developed in which general equation of fluid flow into the isotropic and anisotropic...

in this essay, the metamorphosis technique in animation is treated as a metaphoric structure, using visual or conceptual similarities between two shapes to express poetic imagination. this structure makes metamorphosis technique comparable with poem and dreams.  this project has been carried out using the data available in books, articles and other published documents and movies. the data has b...

AIM In this paper we report on the rates of drug/alcohol use on acute psychiatric wards in relation to levels and intensity of exit security measures. BACKGROUND Many inpatient wards have become permanently locked, with staff concerned about the risk of patients leaving the ward and harming themselves or others, and of people bringing illicit substances into the therapeutic environment. MET...

In budding yeast, exit from the pachytene stage of meiosis requires the mid-meiosis transcription factor Ndt80, which promotes expression of approximately 200 genes. Ndt80 is required for meiotic function of polo-like kinase (PLK, Cdc5) and cyclin-dependent kinase (CDK), two cell cycle kinases previously implicated in pachytene exit. We show that ongoing CDK activity is dispensable for two even...

After sister chromatid splitting at anaphase onset, exit from mitosis comprises an ordered series of events. Dephosphorylation of numerous mitotic substrates, which were phosphorylated by cyclin-dependent kinase (Cdk), is thought to bring about mitotic exit, but how temporal ordering of mitotic exit events is achieved is poorly understood. Here, we show, using budding yeast, that dephosphorylat...