Submit Manuscript | http://medcraveonline.com Abbreviations: MOF: Multiple Organ Failure; DCS: Damage Control Surgery; ISS: Injury Severity Score; GSC: Glasgow Coma Scale; PTT: Prothrombin Time; APTT: Activated Partial Thromboplastin Time; PTL: Platelets; PRBCS: Packed Red Blood Cells; FAST: Focused Abdominal Sonography For Trauma; CT: Computed Tomography; ROTEM: Rotational Thrombelastometry; F...

Obstetric hemorrhage is the leading cause of maternal mortality, responsible of 143,000 deaths every year. Thromboelastography is a tool that allows measuring the viscoelastic, dynamic and global properties of the blood, offering valuable information of coagulation alterations and help to guide early goal directed transfusional therapy. The purpose of this review is to evaluate the evidence of ...

A patient undergoing intracranial surgery developed disseminated intravascular coagulation with life threatening peroperative bleeding. Thromboelastography established the diagnosis of hyperfibrinolysis, usually a fatal complication of a neurosurgical operation. With the administration of a high dose regimen of aprotinin (Trasylol) the haemorrhage was controlled and the hyperfibrinolytic state ...