نتایج جستجو برای: thromboinflammation
تعداد نتایج: 83 فیلتر نتایج به سال:
Immune-inflammatory (autoimmune and autoinflammatory) rheumatic diseases are widespread severe chronic inflammatory also models for studying the fundamental mechanisms of pathogenesis approach to pharmacotherapy other associated with autoimmunity and/or autoinflammation. Uncontrolled inflammation leading hypercoagulation forms basis thromboinflammation, which is considered a universal pathogene...
Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of vascular inflammation. Recent studies highlight the involvement of VWF and its regulator, ADAMTS13, in mechanisms that underlie vascular inflammation and immunothrombosis, like leukocyte rolling, adhesion, and extravasation; vascular permeability; ischemia/reperfusion injury; complements activation; and NETosi...
BACKGROUND AND PURPOSE Admission hyperglycemia is associated with a poor outcome in acute ischemic stroke. How hyperglycemia impacts the pathophysiology of acute ischemic stroke remains largely unknown. We investigated how preexisting hyperglycemia increases ischemia/reperfusion cerebral injury. METHODS Normoglycemic and streptozotocin-treated hyperglycemic rats were subjected to transient mi...
Coronavirus disease 2019 (COVID-19), the currently prevailing pandemic that has besieged whole world, is caused by a novel coronavirus, named as, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially, there was focus on disease, which and most predominant presentation. However, with increasing spread of infection consequent knowledge experience about it become apparent virus w...
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