Trichomoniasis is the most common sexually transmitted disease, caused by a motile flagellate non-invasive parasitic protozoan, Trichomonas vaginalis (T. vaginalis). More than 160 million people worldwide are annually infected by this protozoan. T. vaginalis occupies an extracellular niche in the complex human genito-urinary environment (vagina, cervix, penis, prostate gland, and urethra) to su...

Despite being a readily diagnosed and treated sexually transmitted disease (STD), trichomoniasis is not reportable in the United States, and control of trichomo-niasis has received relatively little emphasis from public health STD control programs, including that of the Centers for Disease Control and Prevention. More recently, however, appreciation of high rates of disease and of associations ...

This study was concerned the describe of an current PCR method for specific detection Tichomonas vaginalis DNA into a rapid nested assay, and to estimate recent prevalence T. according studying different factors that effect on vaginal trichomoniasis in women complaining discharge. Vaginal swab samples were collected from 100 patients lived at Wasit province, during period January, 2022 July, 20...

Neutrophils are the predominant inflammatory cells found in vaginal discharges of patients infected with Trichomonas vaginalis. In this study, we examined superoxide anion (O2 (.-)) production by neutrophils activated by T. vaginalis. Human neutrophils produced superoxide anions when stimulated with either a lysate of T. vaginalis, its membrane component (MC), or excretory-secretory product (ES...

background: trichomoniasis is a worldwide sexually transmitted disease (std), and is associated with important public health problems, including enhancement of hiv transmission. the prevalence of the parasite, trichomonas vaginalis, depends on host factors such as age, sexual activity, number of sexual partners and sexual behavior. the aim of the study was to evaluate the prevalence of trichomo...

Enzyme immunoassay (EIA) was used to detect antibodies to Trichomonas vaginalis in sera from Zimbabwe. The EIA showed a sensitivity of 95 and 94% when compared with vaginal swab culture among women attending a family planning clinic (FPC) and female commercial sex workers (CSW) respectively. The specificity was 85 and 77% in the two groups. Culture-negative FPC women were sub-divided into high ...

Trichomoniasis caused by the parasitic protozoan Trichomonas vaginalis is the most common sexually transmitted disease in the world. Dendritic cells are antigen presenting cells that initiate immune responses by directing the activation and differentiation of naïve T cells. In this study, we analyzed the effect of Trichomonas vaginalis-derived Secretory Products on the differentiation and funct...

BACKGROUND Trichomoniasis, caused by Trichomonas vaginalis, is the most common sexually transmitted disease (STD) in the world with estimates of 7-8 million infections annually in the United States and 180 million globally. OBJECTIVES This study aimed to determine the prevalence and risk factors for T. vaginalis infection in women who attended the Clinic of Obstetrics and Gynecology in Kerman...

Trichomonas vaginalis, a human urogenital tract parasite, is capable of surviving in the male microenvironment, despite of the presence of Zn(2+). Concentrations > 1.6 mM of Zn(2+) have a trichomonacidal effect; however, in the presence of ≤1.6 mM Zn(2+), several trichomonad proteins are up- or down-regulated. Herein, we analyzed the proteome of a T. vaginalis male isolate (HGMN01) grown in the...