Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel disease. Ulcerative colitis is one of the forms of inflammatory bowel disease. A 62-year-old woman who had been treated for ulcerative colitis for 16 years developed pruritic b...

AIMS To ascertain whether the dogma that a normal rectal biopsy precludes a diagnosis of ulcerative colitis is correct. METHODS Rectal biopsy specimens from a prospective group of 24 asymptomatic patients, with an established diagnosis of ulcerative colitis, were examined in a blinded study alongside 10 normal rectal biopsy specimens from an age and sex matched patient cohort without ulcerati...

were measured in 15 patients with ulcerative colitis, 15 patients with Crohn's disease, and 12 normal control subjects. Diminished reactivity to DNCB was demonstrated in 87% of patients with Crohn's disease (p < 0 001) and in 53% with ulcerative colitis (p < 0 02), as compared with only 8-5 % of controls; anergy was more frequent in Crohn's disease than in ulcerative colitis (p < 0 05). Levels ...

BACKGROUND The pathogenesis of ulcerative colitis is unclear, but cytotoxic T lymphocytes infiltrating the mucosa have been implicated in mucosal damage. The Fas ligand (FasL), expressed on cytotoxic T lymphocytes, induces apoptosis in cells expressing Fas. AIM To analyse FasL expression in affected colonic mucosa to ascertain Fas-FasL interaction in ulcerative colitis. METHODS FasL mRNA wa...

conclusions this study showed the importance of considering syndrome differentiation and temperaments in interpreting the effect of p. granatum peels extract on ulcerative colitis. results therapeutic response was significantly higher in patients with hot temperament compared to patients with cold temperament in the p. granatum group (1.916 ± 0.492 versus -0.500 ± 0.500, p = 0.029). methods sev...

Faecal samples were collected from 23 patients with active ulcerative colitis, 15 patients with established ulcerative colitis in remission, 20 patients with active colitis of cause other than ulcerative colitis, and 20 normal control subjects. Ten coliform colonies were randomly selected from the faecal sample cultures and serotyped before the testing of each different serotype from each sampl...

background: the amount of literature concerning the implication of the red cell distribution width (rdw) in the assessment of ulcerative colitis (uc) activity is rather limited. the aim of this study is to investigate the potential role of rdw in the evaluation of uc disease activity. materials and methods: a total of 96 patients with uc and 51 age and sex-matched healthy volunteers were includ...

BACKGROUND AND AIMS Despite numerous shared susceptibility loci between Crohn's disease and ulcerative colitis, the prevalence of family history among ulcerative colitis patients is not well-established and considered to be less prevalent. A systemic review and meta-analysis were conducted to estimate the prevalence of family history of inflammatory bowel disease in ulcerative colitis patients,...

BACKGROUND Ulcerative colitis disease activity indices have not been formally validated. AIM To analise quantitatively the psychometric and performance validity of two non-endoscopic indices for ulcerative colitis, the Simple Clinical Colitis Activity Index and the Seo Index. METHODS In 66 patients with ulcerative colitis, the measurement of disease activity was repeated with the two non-en...