Dear Editor-in-Chief   Lesional histopathological features in pityriasis rosea (PR) are non-specific (1).  Our aim here is to investigate whether a histopathological take-off sign (TOS) is associated with PR.

HHV-6 has been identified as the aetiologic agent of exanthem subitum in infants and an acute febrile illness in young children. HHV-6 probably remains latent in the body after the primary infection and it reactivates upon host immunosuppression in a manner similar to other human herpes viruses. Primary HHV-6 infection in adults is very rare and it is not clear whether disease manifestations ar...

A provisional clinical diagnosis of exanthem subitum was made in six febrile infants seen in the Paediatric Unit of Assunta Hospital, Petaling Jaya, Malaysia with uvulo-palatoglossal junctional ulcers prior to the eruption of maculopapular rash. On follow-up, all six infants developed maculopapular rash with the subsidence of fever at the end of the fourth febrile day. Human herpesvirus 6 was i...

Currently, the incidence of measles and rubella has decreased and the diseases have been eliminated in some countries with high vaccination coverages. Awareness of the clinical manifestations of the two diseases is essential, as there is always the possibility of new cases, which should be suspected on the basis of the medical history and physical examination. The diagnosis is based on clinical...

Although a few textbooks persist in describing separately 'Schonlein's purpura' and 'Henoch's purpura' the recognition of the Schonlein-Henoch syndrome as a disease entity cannot now be disputed. The characteristic exanthem, the frequent occurrence of arthritis and intestinal symptoms, together with the possibility of renal damage, are well known. Serious neurological complications of this cond...