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تعداد نتایج: 4755286 فیلتر نتایج به سال:
the present study set out (a) to examine the categories of pedagogical knowledge related to the act of teaching of novice and experienced teachers as gleaned from their verbal report of what they were thinking about while teaching and (b) to compare the categories of pedagogical knowledge of novice and experienced teachers. the aim of comparing these two groups of teachers was to see whether di...
Critical geopolitics, which has entered the international relations literature since 1975 through the efforts of Frankfurt School theorists, identifies the identity, discourse approach, and importance of informal-state actors. The present article seeks to answer the question of whether it is possible to use critical geopolitical theory in the analysis of the foreign policy of the Islamic Republ...
Experimental models that mimic the flow conditions in microcapillaries have suggested that the local shear stresses and shear rates can mediate tumor cell and leukocyte arrest on the endothelium and subsequent sustained adhesion. However, further investigation has been limited by the lack of experimental models that allow quantitative measurement of the hydrodynamic environment over adherent ce...
The aim of this study is to determine what factors constitute a quality prosthesis and ascertain which factors affect prosthesis satisfaction. Sixty-four women who received full funding for their prosthesis and 38 women who received their hospital's usual funding were recruited. Women rated the information provided about breast prostheses very highly, with 85% reporting that it was "very good" ...
The importance of invasion in the complex process of metastasis, although now well established, has been studied with increasing molecular detail due to the development of robust in vitro experimental assays. In this issue of Cancer Research, we highlight a paper published by George Poste and colleagues that compared and contrasted several different invasion assays. The authors concluded that v...
Both referees agree that your results are novel, important and of broad interest. However, both have serious concerns about the strength of the conclusions you are able to draw from your current experiments and ask that you undertake work to improve the evidence presented. Both agree that your final conclusion, that CD95 stimulation activates PLCgamma1 via PDGFR, is not yet well supported by th...
Compelling evidence indicates Type I CD20 immunotherapeutic mAbs promote targeted tumor cell elimination exclusively via immune effector functions, which can be exhausted/saturated. mAb dosing paradigms should therefore take into account the capacity of these cytotoxic mechanisms, leading to the conclusion that lower doses, given frequently, may be far more effective.
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