Two new simple and selective assay methods have been presented for the analysis of eprosartan mesylate (EPR) and hydrochlorothiazide (HCT) in pharmaceutical formulations. The first method is based on first-derivative ultraviolet spectrophotometry with zero-crossing measurements at 246 and 279 nm for EPR and HCT, respectively. The assay was linear over the concentration ranges 3.0-14.0 µg/mL for...

Possibility of application of wavelet analysis in EPR spectroscopy is investigated. Basic mathematics of the method is summarized, with emphasis on the relation between EPR experiment and physical interpretation of wavelet transform. The fact that first derivative of the Lorentzian function can be used as a base wavelet is employed and the specific rules of the interpretation of the final wavel...

Many properties of a material, such as physical shape, crystalline or amorphous form, and particle size, may affect the quality of EPR response. The effects of mechanical treatment to a material such as grinding, crushing, and particle size on EPR signal were reported earlier [1, 9]. The EPR technique is a well known and well established method for dose measurement in several fields like radiat...

Electron paramagnetic resonance (EPR)-based oximetry is capable of quantifying oxygen content in samples. However, for a heterogeneous environment with multiple pO2 values, peak-to-peak linewidth of the composite EPR lineshape does not provide a reliable estimate of the overall pO2 in the sample. The estimate, depending on the heterogeneity, can be severely biased towards narrow components. To ...

A method of post-processing to enhance the image resolution of the distribution of free radical molecules obtained with continuous-wave electron paramagnetic resonance (CW-EPR) imaging is reported. The low spatial resolution of EPR imaging, which has created difficulties in biomedical applications, was overcome by the method of resolution-recovery for EPR imaging. High spatial resolution images...

A one-dimensional electron paramagnetic resonance (EPR) imaging method for visualisation of dose distributions in photon fields has been developed. Pressed pellets of potassium dithionate were homogeneously irradiated in a (60)Co radiation field to 600 Gy. The EPR analysis was performed with an X-Band (9.6 GHz) Bruker E540 EPR and EPR imaging spectrometer equipped with an E540 GC2X two-axis X-b...

Ionizing radiation is useful for the conservation and disinfestation of fresh and dried fruits. The treatment of fruits with gamma-rays or beams of accelerated electrons has been carefully tested and was recommended by FAO/WHO Codex Alimentarius Commission for the common use as an effective and safe preservation method [1]. It was found earlier that the ionizing radiation produces stable EPR si...