This study evaluated an enzyme immunoassay (EIA) as a screening tool for detection of the most common mutation (delta F508) in cystic fibrosis (CF). Guthrie card bloodspots were extracted to remove whole blood polymerase chain reaction (PCR) inhibitors. The washed filter paper was directly amplified under standard (98 bp amplicons) or modified PCR conditions (491 bp amplicons) for the delta F50...

Associated Press W rite r__________________ SOUTH BEND The dark industria l factories along the St. Joseph River that were once the hallmark of this c i ty ’ s d ow n tow n are gone. Gone, too, are the high-paying m anufacturing jobs at compa­ nies such as Studebaker and Bendix. Now the downtown is filled w ith men and w om en who dress in business su its and work in professional or serviceorie...

Propagation in l inear planar wa vegui des is a wel l-known pro blem , whereas pro pagati on in nonl inear waveguides wa s considered onl y in parti cular cases. Tha t is the caseof the nonl inear waveguide wi th a l inear Ùlm on a nonl inear substra te [1], then the l inear Ùlm surro unded by the nonl inear substra te and cover [2{ 7], the nonl inear Ùlm surro unded by l inear isotro pi c m ed...

Persian language is one of the most widely used languages in the Web environment. Hence, the Persian Web includes invaluable information that is required to be retrieved effectively. Similar to other languages, ranking algorithms for the Persian Web content, deal with different challenges, such as applicability issues in real-world situations as well as the lack of user modeling. CF-Rank, as a ...

Five different parameters, time of incubation of the culture, type of culture medium, inoculum, strain of inbred mice, and age of mice, were tested using the LD50 technique to standardize a murine model for the evaluation of the virulence of Streptococcus suis capsular type 2 isolates. A model using 28 day-old mice belonging to CF1 strain appeared to give the best results. The inoculum size was...

Goodchild, M. C., Murphy, G. M., Howell, A. MA, Nutter, S. A., Anderson, C. M. (1975). Archives of Disease in Childhood, 50, 769. Aspects of bile acid metabolism in cystic fibrosis. Previous reports have indicated that cystic fibrosis (CF) patients with pancreatic enzyme insufficiency have a raised faecal bile acid output. In this study, 18 out of 29 CF patients and 2 out of the 4 non-CF patien...

To better understand how airways produce thick airway mucus, nonvolatile solids were measured in liquid secreted by bronchi from normal pig, cystic fibrosis (CF) human, and non-CF human lungs. Bronchi were exposed to various secretagogues and anion secretion inhibitors to induce a range of liquid volume secretion rates. In all three groups, the relationship of solids concentration (percent nonv...