The nematode Caenorhabditis elegans is a powerful model organism to study functions of polyunsaturated fatty acids. The ability to alter fatty acid composition with genetic manipulation and dietary supplementation permits the dissection of the roles of omega-3 and omega-6 fatty acids in many biological process including reproduction, aging and neurobiology. Studies in C. elegans to date have mo...

The omega-3 fatty acids are essential dietary nutrients and one of their important roles is providing the fatty acid with 22 carbons and 6 double bonds known as docosahexaenoic acid (DHA) for nervous tissue growth and function. Inadequate intakes of omega-3 fatty acids decrease DHA and increase omega-6 fatty acids in the brain. Decreased DHA in the developing brain leads to deficits in neurogen...

Background: Beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on the male fertility are widely described in the literature. However, there is little information about the effect of dietary n-3/n-6 ratios and Vit E on the male reproduction. The aim of this study was to evaluate the influence of dietary PUFAs on the rat sperm characteristics after eight weeks oil consumption. Mate...

OMEGA-3 FATTY ACIDS ARE KEY Our brain and nerves are composed mostly of fat. The most important of these are called omega-3 fatty acids and are found primarily in fish or fish oil supplements. Also called EPA and DHA, they are absolutely necessary for human health, and their concentration in the brain makes them key players in neurological disorders such as autism and ADHD. Brain and nerve grow...

There is substantial evidence that omega-3 fatty acids reduce blood pressure, with a greater effect in hypertensive patients and those with high-normal blood pressure. The dose of omega-3 fatty acids required to achieve a blood pressure reduction is likely to be at least 3-4 g/day. However, the magnitude of the blood pressure change can be increased by salt restriction or when omega-3 fatty aci...

Two omega-3 fatty acids including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are essential for the physiologic function of neuronal cell membrane. Normal function of neuronal cell membrane requires appropriate composition of fatty in its structure. Present study was designed to compare the effect of short-term and long-term pretreatment with omega-3 fatty acids on scopolamine-in...

abstract background: migraine is a primary headache disorder that affects the neurovascular system. recent studies have shown that consumption of some fatty acids such as omega‑3 fatty acids improves migraine symptoms. the aim of the present study is to assess the association between usual intake of fatty acids such as eicosapentaenoic acid (epa), docosahexaenoic acid (dha), and saturated fatty...