Adiponectin, a hormone secreted from adipocytes, is closely associated with psoriasis and suppresses psoriasiform inflammation. Recently, small-sized transdermally deliverable 5-mer peptide (GLYYF; P5) was discovered as potential adiponectin receptor 1 agonist. This study aims at confirming the reduction of protein level in human skin investigating whether functional replenishment by topical P5...

Background & Objectives: Several epidemiological studies have indicated factors such as Leptin level, Adiponectin and plasma adiponectin-to-leptin index to be the predicting biomarkers for cardiovascular diseases. Given the importance of healthy nutrition and adequate exercise in reducing the risk of Atherosclerosis, this study aimed to investigate the effects of fasting and aerobic exercise on...

background: regular physical exercise is a well-established therapeutic option to prevent the diabetes mellitus. the purpose of this study was to examine the effects of intense interval training (sit (and combined aerobic-strength training on serum adiponectin level and insulin resistance  in women with type 2 diabetes. materials and methods: female patients with type 2 diabetic (n=52, age: 45-...

adiponectin is one of the most important members of adipokine family which is widely synthesized and secreted by adipose tissue. the action of adiponectin is via binding to main receptors. it has several actions including regulation of glucose level, lipid homeo­stasis and reproductive system. adiponectin can also influence vascular endothelium via preventing the migration of monocytes. the rol...

Introduction: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with still growing incidence among adults and young people worldwide. Patients T2DM are more susceptible to develop coronary artery (CAD) than non-diabetic individuals. Several pre-clinical clinical studies suggested that adiponectin, pleiotropic hormone anti-atherogenic, anti-inflammatory, insulin-sensitizing properti...