Human somatic stem cells with neural differentiation potential can be valuable for developing cell-based therapies, including treatment of birth-related defects, while avoiding issues associated with cell reprogramming. Precisely defining the "identity" and differentiation potential of somatic stem cells from different sources, has proven difficult, given differences in sets of specific markers...

Mesenchymal stem cells (MCSs) from adipose tissue are reported to have a pronounced impact on tumor growth or suppression. However, so far, how the cancer affect in vivo conditions has not been clarified. In this study, we evaluated of breast characteristics adipose-derived (ADSCs) under conditions. ADSCs were obtained Balb/c mice three consecutive weeks after transplantation with 1×106 MCF7 ce...

BACKGROUND Mesenchymal stem cells (MSCs), including adipose tissue-derived mesenchymal stem cells (ADSC), are multipotent and can differentiate into various cell types possessing unique immunomodulatory features. Several clinical trials have demonstrated the safety and possible efficacy of MSCs in organ transplantation. Thus, stem cell therapy is promising for tolerance induction. In this study...

Mesenchymal stem cells from several sources (bone marrow, synovial tissue, cord blood, and adipose tissue) can differentiate into variable parts (bones, cartilage, muscle, and adipose tissue), representing a promising new therapy in regenerative medicine. In animal models, mesenchymal stem cells have been used successfully to regenerate cartilage and bones. However, there have been no follow-up...

Diabetes mellitus (diabetes) is a devastating disease that affects millions of people globally and causes a myriad of complications that lead to both patient morbidity and mortality. Currently available therapies, including insulin injection and beta cell replacement through either pancreas or pancreatic islet transplantation, are limited by the availability of organs. Stem cells provide an alt...

skeletal muscle is a highly differentiated tissue with very specific functions which has low potential of regeneration. skeletal muscle injuries especially in athletes almost have lead to muscular dysfunctions and healing may be prolonged for several years. therefore, working on skeletal muscle differentiation remained an importance in biomedical researches. adipose derived stem cells (adscs) a...

bachgroun: hematopoietic stem cell derived from umbilical cord blood (ucb) has been used for regenerative medicine in hematological abnormalities. micrornas are important regulators of gene expression that control both physiological and pathological processes such as development of tissue and cancer. some studies have shown that mir-33, has a critical role in control of self-renewal cells. here...

Introduction: Previous studies have proven that secretory materials of mesenchymal stem cells (MSCs) (secretome) remedial properties. Objectives: The main goal this study was to evaluate the effects secretome adipose-derived MSCs on growth and apoptosis in anaplastic thyroid carcinoma (ATC) C-643 cells. Materials Methods: Initially, were exposed 25 50 μg/mL (ADSCs) for 24 48 hours, proliferatio...