Allergic asthma is the most common acute inflammatory airway disorder and their incidence population has exploded in the last years, being estimated that over 300 million people worldwide have the condition. Here, we present a brief overview of relationship of allergic asthma with diet and food intake. Several studies have shown that most asthma cases are due to an allergic immune response to e...

The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

This issue of Asia Pacific Allergy (Asia Pac Allergy) will be released at the beginning of its third year of circulation. Asia Pac Allergy is just two years old yet very active and on the way to developing into a leading publication in allergic disease research. We thank all the authors and readers for their efforts and contributions. Our current issue features two valuable reviews on the topic...

Used as models on restricted nasal respiration, 11 individuals with a unilateral inborn occlusion of the nose were examined with regard to growth of the mid-facial skeleton. The preference to oral breathing, also a fairly constant feature in patients with chronic or allergic rhinitis with hyperplasia of the pharynx tonsil, appeared to result in a significant underdevelopment of the maxilla in t...

Background Enhanced eosinophil extravasation into the tissue is a characteristic feature of bronchial asthma and other allergic diseases. The barrier-forming vascular endothelial cells release prostaglandin I2 (PGI2, prostacyclin) as the major prostanoid, and it has been previously observed that PGI2 receptor (IP)-deficient mice show enhanced eosinophilic inflammation in response to allergens. ...

Background Eosinophilic infiltration into the tissues of the airway is a central feature of aspirin-exacerbated respiratory disease (AERD). Eosinophil activation and survival are profoundly influenced by IL-5 and its receptor, IL-5R. In patients susceptible to allergic disorders, IL5RA polymorphisms have been reported, however, an association with AERD remains unclear. We hypothesise that the p...

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