The role of the aldose reductase in type 2 diabetes is widely described. Therefore, it is of interest to identify plant derived compounds to inhibit its activity. We studied the protein-ligand interaction of 267 compounds from different parts of seven plants (Allium sativum, Coriandrum sativum, Dacus carota, Murrayyakoneigii, Eucalyptus, Calendula officinalis and Lycopersicon esculentum) with a...

A combination of crushed garlic (Allium sativum sativum) has been used as a traditional remedy for antimicrobial testing suggested that the mixture of tw antimicrobial effects on both Staphylococcus aureu Analyses of the extract of garlic and black cumin by G confirmed that the main components of garlic were allic allicin transformed products such as diallyldisulfide a black cumin were thymoqui...

Isolation of a number of bioactive compounds from medicinal plants such as acetylcholinesterase inhibiting steroidal alkaloids, homomoenjodaramine and moenjodaramine from Buxus hyrcana, anti-epileptic terpenoids delphadienones I and II from Delphinium denudatum, and potent leishmanicidal compound ajoene from Allium sativum have been achieved through bioactivity-guided isolation.

OBJECTIVE The schistosomicidal properties of garlic (Allium sativum) and onion (Allium cepa) powder were tested in vitro against Schistosoma mansoni miracidia, schistosomula, cercaria and adult worms. Results indicate their strong biocidal effects against all stages of the parasite and also show scavenging inhibitory effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide (NO). MATERI...

Antioxidant activity of fresh Allium sativum L. (garlic) is well known and is mainly due to unstable and irritating organosulphur compounds. Fresh garlic extracted over a prolonged period (up to 20 months) produces odourless aged garlic extract (AGE) containing stable and water soluble organosulphur compounds that prevent oxidative damage by scavenging free radicals. The aim of this study was t...

Thirty strains of mycobacteria, consisting of 17 species, were inhibited by various concentrations of garlic extract incorporated in Middlebrook 7H10 agar. The concentration required ranged from a low of 1.34 mg/ml to a high of 3.35 mg/ml of media. When there were multiple strains of a species, a mean inhibitory concentration was determined for that species. Six strains of Mycobacterium tubercu...

background & aim: allium sativum commonly known as garlic is an herb used over years to prevent from various ailments such as cardiovascular diseases, cognitive disorders and also enhances the immune system. the aim of the present study is to study the in vitro antiarthritic and antihemolytic potential of garlic in aqueous and methanolic extracts. fourier transform infrared spectroscopy was per...

objective(s): trichophyton rubrum (t. rubrum) is one of the most common dermatophytes worldwide. this fungus invaded skin appendages of humans and animals. recently, resistance to antifungal drugs as well as appearance of side effects due to indication of these kinds of antibiotics has been reported. besides, using some plant extracts have been indicated in herbal medicine as an alternative tre...