نتایج جستجو برای: amyloid precursor protein processing

تعداد نتایج: 1764108  

Journal: :Neurobiology of disease 2005
Elena M Ribé Mar Pérez Berta Puig Ignasi Gich Filip Lim Mar Cuadrado Teresa Sesma Silvia Catena Belén Sánchez María Nieto Pilar Gómez-Ramos M Asunción Morán Felipe Cabodevilla Lluis Samaranch Lourdes Ortiz Alberto Pérez Isidro Ferrer Jesús Avila Teresa Gómez-Isla

Even though the idea that amyloid beta peptide accumulation is the primary event in the pathogenesis of Alzheimer's disease has become the leading hypothesis, the causal link between aberrant amyloid precursor protein processing and tau alterations in this type of dementia remains controversial. We further investigated the role of beta-amyloid production/deposition in tau pathology and neuronal...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده کشاورزی 1390

abstract this study is carried out to determine the chemical composition in the three vegetative stages of the haloxylon sp., degradation parameters, with adding naoh and ca(oh2 ). for this purpose, in may and october and january 2010 enough some haloxylon sp. of the ammary area was prepared. crude protein and ash percentage are decrease, neutral detergent fiber percentage with pragress stage ...

2007
Linda Adlerz

Alzheimer’s disease (AD) is today the most common form of dementia. It is a neurodegenerative disorder which is histopathologically characterised by amyloid plaques and neurofibrillary tangles. Amyloid plaques consist of the amyloid β-peptide (Aβ) that can form aggregates in the brain. Aβ is generated from the amyloid precursor protein (APP) through proteolytic cleavage. APP belongs to a conser...

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