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objective(s):an earlier meta-analysis on gene expression data derived from four microarray, two cdna library, and one sage experiment had identified rgs5 as one of only ten non-housekeeping genes that were reported to be expressed in human trabecular meshwork (tm) cells by all studies. rgs5 encodes regulator of g-protein signaling-5. the tm tissue is the route of aqueous fluid outflow, and is r...
Introduction: The prediction of microRNAs related to target genes using bioinformatics tools saves time and costs of the experimental analyses. In the present study, the prediction of microRNA target genes relevant to Alzheimer’s Diseases (AD) were compared with the experimentally reported data using different bioinformatics tools. Method: A total of 41 microRNAs associated with 21 essential ge...
Introduction: The prediction of microRNAs related to target genes using bioinformatics tools saves time and costs of the experimental analyses. In the present study, the prediction of microRNA target genes relevant to Alzheimer’s Diseases (AD) were compared with the experimentally reported data using different bioinformatics tools. Method: A total of 41 microRNAs associated with 21 essential ge...
In this paper, the continuity of tracking a ground moving target using a Hexarotor is considered in the presence of sudden changes in direction, deceptive movements, temporary departure from the field of view (FOV) and changes in the height of the target. In this regard, a hierarchical guidance and control system for target tracking problem in an unknown environment and disturbances is proposed...
the current building codes provide limited prescriptive guidance on design for protection of buildings due to progressive collapse. progressive collapse is a situation in which a localized failure in a structure, caused by an abnormal load, such as explosions or other happenings. three procedures, often employed for determination of the structural response during progressive collapse i.e. linea...
Objective(s): Detection of circulating Mycobacterium tuberculosis (M. tuberculosis) antigens is promising in Tuberculosis (TB) diagnosis. However, not a single antigen marker has been found to be widely expressed in all TB patients. This study is aimed to prepare broadly reactive polyclonal antibodies targeting multiple antigen markers (multi-target antibodies) and evaluate their efficacies in ...
PURPOSE The geometrical uncertainties in the patient positioning during intensity modulated radiotherapy (IMRT) are crucial as there is potential to underdose the tumor and overdose the nearby critical structures. Image guided techniques provide a solution to assess the patient set-up uncertainties and help determine the optimal planning target volume (PTV) margin to the clinical tumor volume (...
The name “Brachytherapy” is derived from ancient Greek words for short distance (brachios) and treatment (therapy) and refers to the therapeutic use of encapsulated radionuclides placed within or close to the tumor. Brachytherapy (BT), used as an integral part of cancer treatment for almost a century, developed in last three decades a rapid growth with the development of afterloading devices an...
background: most preclinical studies are carried out on mice. for internal dose assessment of a mouse, specific absorbed fraction (saf) values play an important role. in most studies, saf values are estimated using older standard human organ compositions and values for limited source target pairs. objective: saf values for monoenergetic photons of energies 15, 50, 100, 500, 1000 and 4000 ke...
The International Commission on Radiation Units and Measurements Report 62 (ICRU 1999) introduced the concept of expanding the clinical target volume (CTV) to form the planning target volume by a two-step process. The first step is adding a clinically definable internal margin, which produces an internal target volume that accounts for the size, shape and position of the CTV in relation to anat...
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