The bactericidal capacity of digestion products of bovine milk triglycerides and membrane lipids was tested in vitro using Escherichia coli O157:H7, Salmonella enteritidis, Campylobacter jejuni, Listeria monocytogenes, and Clostridium perfringens. C10:0 and C12:0 fatty acids and digestion products of sphingolipids appeared to be effective bactericidal agents, whereas digestion products of phosp...

The bactericidal activity of moxifloxacin alone and in combination with cefepime or piperacillin-tazobactam against clinical isolates of Klebsiella pneumoniae, Enterobacter cloacae, and Acinetobacter baumannii was evaluated by using time-kill methods and antimicrobial concentrations of one-half and one times the MIC. Synergy was observed in 58 to 88% of the strains and resulted in bactericidal ...

Low concentrations of hemoglobin (0.1 microg./ml. or less) exert a lethal action on some Gram-negative bacteria under certain conditions in vitro. Hemoglobins from various mammals and the distinct genetic types of human hemoglobin all manifest similar bactericidal activity. The bactericidal effect is a function of the globin moiety of the molecule; native and acid or acid-alcohol denatured glob...

conclusions results of this study suggest that the extract alone of peganum harmala and heracleum persicum may be useful to treat bacterial infections. objectives the major aim of the current study was to investigate the antimicrobial activity of an extract of the peganum harmala flower and heracleum persicum against acinetobacter baumannii. materials and methods the minimum inhibitory (mic) co...

in  this  reaserch,  photocatalyst  titanium  dioxide  was  doped  with silver  and modified  by  polyethylene  glycol  by  sol  gel method  and the  samples  were  characterized  by  x-ray  diffraction  (xrd)  and scanning  electron  microscopy  (sem).  the  purpose  of  the  present study  was  to  evaluate  the  photocatalytic  bactericidal  effects  of prepared nanocomposite on human pathog...

Bactericidal antibody is required for direct complement-mediated killing of most pathogenic gram-negative bacteria. Although it has been implicitly assumed that bactericidal antibody functions by increasing complement activation and deposition on the bacterial surface, this assumption may not be valid. We have shown previously (1) that bactericidal IgG increases the bactericidal efficiency of C...

Bactericidal testing historically has exhibited variable reproducibility, even when prior standardized methods were employed. Several modifications to the National Committee for Clinical Laboratory Standards (NCCLS) broth macrodilution method are proposed to improve reproducibility. Recommended changes from the approved NCCLS guidelines (M21-A and M26-A) include omitting serum supplementation o...

OBJECTIVES We investigated the bacteriostatic and bactericidal activities of piperacillin/tazobactam against 16 clinical Escherichia coli producing inhibitor-resistant TEM β-lactamases (IRT; 13/16) and complex mutant TEM enzymes (CMT; 3/16). METHODS Bacteriostatic activity was evaluated by three methods (disc diffusion, Vitek2 automated system, MIC determination by a microdilution method) and...