A micromethod for performance of the serum bactericidal test is described, and the results obtained with this method are compared with those obtained with the standard tube dilution macromethod. An agreement within +/- 1 dilution was achieved in 23 of 25 (92%) determinations of the serum bactericidal titer. The micromethod used approximately one-third of the amount of pooled normal human serum ...

objective: this study aims to evaluate the antimicrobial activity, phytochemical studies and thin layer chromatography analysis of machine oil, hexane extract of seed oil and methanol extract of presscake& latex of jatropha curcas linn (family euphorbiaceae). materials and methods: j. curcas extracts were subjected to preliminary qualitative phytochemical screening to detect the major phytochem...

objective(s): cuo is one of the most important transition metal oxides due to its captivating properties. it is used in various technological applications such as high critical temperature superconductors, gas sensors, in photoconductive applications, and so on. recently, it has been used as an antimicrobial agent against various bacterial species. materials and methods: here, we synthesized cu...

The aim of this study was to investigate respondents' satisfaction with smart device-based testing (SBT), as well as its convenience and advantages, in order to improve its implementation. The survey was conducted among 108 junior medical students at Kyungpook National University School of Medicine, Korea, who took a practice licensing examination using SBT in September 2015. The survey contain...

the nanomaterials have important application in different field of science such as biology and pharmacology, which draws the attention of biologists towards this field of study more than before. as the worldwide mortality rate is high due to the pathogens and especially because of the bacteria associated dysenteriae and the antibacterial effect of metal nanoparticles is well known from centurie...

benzalkonium chloride is a quaternary ammounium compounds derivative under different names such as afxhang, hamoon, mahan etc, which have great and expanded use in sanitation and medical affairs. bactericidal activity of these disinfectants was fulfilled according to national standard method no.2842 on staph. aureus, sal. typhimouium and e. coli. this laboratory test showed that, except mahan t...

BACKGROUND In this investigation, the urine samples obtained in a single oral-dose pharmacokinetic study were examined for their bactericidal activity against a range of relevant urinary tract pathogens. METHODS Six healthy volunteers received a single oral dose of ten oral antibiotics available in Croatia. Urine samples were taken every 2 h during the whole dosing interval of the particular ...

Questionnaires were sent to 37 diagnostic microbiology laboratories to assess their methods for performance of the serum bactericidal test. Of the 28 responding laboratories, 26 utilized the test, with considerable variation among methods. Culture and dilution media included Trypticase soy, Mueller-Hinton, brain heart infusion, Columbia broth, dextrose phosphate, and pooled human serum. Several...

OBJECTIVES Bactericidal activity depends on antibiotic-bacteria couples, resistance phenotype and theoretically on protein binding. This work explores the influence of protein binding on the bactericidal activity of two antibiotics, daptomycin versus vancomycin, that exhibit, respectively, different C(max) (56 versus 25.5 mg/L), protein binding (91.7% versus 36.9%) and thus theoretical free-dru...