Vertebrate gap junctions are aggregates of transmembrane channels which are composed of connexin (Cx) proteins encoded by at least fourteen distinct genes in mammals. Since the same Cx type can be expressed in different tissues and more than one Cx type can be expressed by the same cell, the thorough identification of which connexin is in which cell type and how connexin expression changes afte...

Technologies advanced in communication devices and wireless networks enable telecommunication network operators to provide rich personalized multimedia services. To attract potential customers and increase average revenue per customer, network operators will provide personalized services as differentiating factors in the near future. To accommodate the diversity and complexity of future network...

This paper presents an innovative portable chip-based RT-PCR system for amplification of specific nucleic acid and detection of RNA-based viruses. The miniature RT-PCR chip is fabricated using MEMS (Micro-electro-mechanical-system) techniques, and comprises a micro temperature control module and a PDMS (polydimethylsiloxane)-based microfluidic control module. The heating and sensing elements of...

With the advent of new RT-level design and test flow, new tools are needed to migrate at the RT-level the activities of fault simulation, testability analysis, and test pattern generation. This paper focuses on fault simulation at the RT-level, and aims at exploiting the capabilities of commercial VHDL simulators to compute faulty responses without modifying the VHDL source code. The proposed a...

The Modeling and Simulation-Driven Engineering (MSDE) approach relies on simulation-based modeling for developing components of real-time embedded systems. We propose the use of the DEVS formalism for MSDE activities. We present the MSDE of an application using incremental development, seamlessly integrating hardware components with models simulated in CD++, a DEVS modeling simulation tool. We ...

In this paper, we propose and present Real-Time Channel-based Reeective Memory (RT-CRM) { a useful programming model and middleware communication service for constructing distributed real-time industrial monitoring and control applications on commercially available open systems. RT-CRM provides remote real-time data reeection abstraction using a simple writer-push model. This writer-push approa...

During 2009-10, real time RT-PCR and conventional RT-PCR techniques Used for detecting BTVs RNA in 310 blood samples. For real time and gel based RT-PCR segment-1 and segment-10 selected as conserve genes to search any BTV strains. Using these methods, 58 (%18.7) and 14 (%4.5) positive samples were detected among the clinically suspected sheep. Sensitivity of both molecular techniques evalua...

Gen ekspresyonunun post-transkripsiyonel düzenleyicisi olarak bilinen miRNA’lar ökaryotik canlılarda çeşitli fizyolojik ve patolojik süreçlerde rol oynamaktadır. miRNA'ların rollerinin ortaya konulması ile birlikte üzerine yapılan çalışmaların sayısı da gün geçtikçe artmaktadır. Yapılan çalışmalar bütün hücre doku tiplerinde eksprese olduğu konmuştur. miRNA ekspresyon profilinin konması için yö...