Radioisotopes that emit electrons (beta particles), such as radioiodine, can effectively kill target cells, including cancer cells. Aqueous 32P[PO4] is a pure beta-emitter that has been used for several decades to treat non-malignant human myeloproliferative diseases. 32P[PO4] was directly compared to a more powerful pure beta-emitter, the clinically important 90Y isotope. In vitro, 32P[PO4] wa...

The radiation detection systems employed in radioanalytical chemistry laboratories have changed considerably over the past sixty years, with significant improvement realized since the early 1980s. Advancements in the areas of material science, electronics, and computer technology have contributed to the development of more sensitive, reliable, and user-friendly laboratory instruments. The four ...

NHL is the most common hematologic cancer in adults. Rituximab is the FDA approved treatment of relapsed or refractory low grade B-cell Non-Hodgkin Lymphoma (NHL). But patients eventually become resistant to rituximab. Since lymphocytes and lymphoma cells are highly radiosensitive, low grade NHL that has relapsed or refractory to standard therapy is treated by RIT in which a beta-emitting radio...

The first nuclear explosion test, named the Trinity test, was conducted on July 16, 1945 near Alamogordo, New Mexico. In the tremendous heat of the explosion, the radioactive debris fused with the local soil into a glassy material named Trinitite. Selected Trinitite samples from ground zero (GZ) of the test site were investigated in detail for radioactivity. The techniques used included alpha s...

Marine luminous bacteria were used to monitor toxicity of alpha(Am-241, U-235+238) and beta(tritium) radionuclide solutions. Increase or inhibition of bacterial luminescence was observed under exposure to radionuclides. Radiation toxicity of Am and chemical toxicity of U were demonstrated. Effects of U were similar to those of stable heavy metals: sensitivy was about 10M. Sensitivity of the bac...

The growing need to quantitate alpha emitting radionuclides in the environment and in nuclear fuel processing and disposal has resulted in dramatic increases in gross alpha/gross beta measurements. In fact, gross alpha/gross beta counting has become the most widely used method of monitoring for the presence of radioactivity. Much of the interest is due to the need to address safety, regulatory ...

Background and Objective: The most common intravascular brachytherapy sources include 32P, 188Re, 106Rh and 90Sr/90Y. In this research, skin absorbed dose for different covering materials in dealing with these sources were evaluated and the best covering material for skin protection and reduction of absorbed dose by radiation staff was recognized and recommended.Method: Four materials including...

PURPOSE The objective of this study is to evaluate requirements for radionuclide-based solid tumor therapy by assessing the radial dose distribution of beta-particle-emitting and alpha-particle-emitting molecules localized either solely within endothelial cells of tumor vasculature or diffusing from the vasculature throughout the adjacent viable tumor cells. METHODS Tumor blood vessels were m...

background: the formalism recommended by task group 60 (tg-60) of the american association of physicists in medicine (aapm) is applicable for β sources. radioactive biocompatible and biodegradable 153sm glass seed without encapsulation is a β- emitter with a short half life and delivers a high dose rate to the tumor in the millimeter range. in this work the dosimetry parameters of the seed for ...

The efficient characterization of nuclear waste materials represents a significant challenge during nuclear site decommissioning, with a range of radionuclides requiring measurement in varied and often complex sample matrices. Of the available measurement techniques, inductively coupled plasma mass spectrometry (ICP-MS) has traditionally been applied to long-lived radionuclides, particularly in...