نتایج جستجو برای: binding effects

تعداد نتایج: 1912460  

Drug delivery by nanomaterials is an active emergent research area and CNTs draws considerable potential application owing to its unique quasi one-dimensional structure and electronic properties. Single walled carbon nanotubes and carbon fullerenes can be used in drug delivery due to their mechanical and chemical stability. The past few years, increasing attention by several reputed groups has ...

Journal: :journal of nanostructures 2012
m. oftadeh n. madadi mahani r. bahjatmanesh ardakani

linear–dendrite copolymers containing hyper branched poly(citric acid) and linear poly(ethylene glycol) blocks pca–peg–pca are promising nonmaterial to use  in nanomedicine. to investigate their potential application in biological systems (especially for drug carries) oniom2 calculations were applied to study the nature of particular interactions between drug and the polymeric nanoparticles.  b...

Journal: :iranian journal of parasitology 0
m niyyati department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran s rezaie department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran z babaei department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran m rezaeian department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran

background: acanthamoeba keratitis develops by pathogenic acanthamoeba such as a. pal­es­tinen­sis . indeed this species is one of the known causative agents of amoebic keratitis in iran. mannose binding protein (mbp) is the main pathogenicity factors for developing this sight threatening disease. we aimed to characterize mbp gene in pathogenic acanthamoeba isolates such as a. palestinensis . m...

Journal: :molecular biology research communications 2014
béla a. marosi karen m. kiemnec-tyburczy ioan v. ghira tibor sos octavian popescu

immune genes of the major histocompatibility complex (mhc) are among the most polymorphic genes in the vertebrate genome. due to their polymorphic nature, they are often used to assess the adaptive genetic variability of natural populations. this study describes the first molecular characterization of 13 partial mhc class iib sequences from three european ranid frogs.  the utility of previously...

Journal: :iranian journal of basic medical sciences 0
abbas shirdel internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran houshang rafatpanah immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran centre for integrated genomic medical research (cigmr), the university of manchester, manchester, uk hassan rahimi internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran abdol rahim rezaee immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran mahmoud reza azarpajooh neurology department, ghaem hospital, mashhad university of medical sciences, mashhad, iran

introduction genetic background has known to be associated with the outcome of human t cell lymphotropic virus (htlv) type i infection. in the present study we investigate the association between gm-csf gene polymorphisms with the outcome of htlv-i infection. materials and methods we analyzed 3 single-nucleotide polymorphisms in the promter region of granulocyte macrophage colony stimulating fa...

عجمی, ابوالقاسم, امجدی, ام‌البنین, حسینیان, عارف , رفیعی, علیرضا, صفایی, سمانه, عابدینی, محمود ,

Interferons (IFNs) are pleotropic cytokines with strong anti-viral and immunomodulatory properties. Their function is dependent to signaling pathway upon binding to IFN receptor. Both pro- and anti-inflammatory effects are seen in interferons-related immune responses. While, interferons are in direct correlation with autoantibodies production during autoimmunity, they have protective effects. T...

Stability of the π-π stacking interactions in the Ben||N-substituted-coronene complexes was studied using the computational quantum chemistry methods (where Ben is benzene and || denotes π-π stacking interaction, and N-substituted-coronene is coronene molecule which substituted with different number of N atoms). The results reveal simultaneous effects of structure and number of Heteroatom on th...

1996
D. Indumathi

The effects of nuclear binding on nuclear structure functions have so far been studied mainly at fixed target experiments, and there is currently much interest in obtaining a clearer understanding of this phenomenon. We use an existing dynamical model of nuclear structure functions, that gives good agreement with current data, to study this effect in a kinematical regime (low x, high Q) that ca...

M Amir Bakhtiarvand M Rezaei Tavirani S Hesami Takallu SH Kalantari SM Mahdavi

Human serum albumin (HSA) is the most abundant plasma protein in the human body. HSA plays an important role in drug transport and metabolism. This protein has a high affinity to a very wide range of materials, including metals such as Cu2+ and Zn2+, fatty acids, amino acids and metabolites such as bilirubin and many drug compounds. In this study, we investigated the effects of co-amoxiclav, as...

Stability of the ;-; stacking interactions in the substituted-coronene||cyclooctatetraene complexes wasstudied using the computational quantum chemistry methods (where || denotes ;–; stackinginteraction, and substituted-coronene is coronene which substituted with four similar X groups; X =OH, SH, H, F, CN, and NO). There are meaningful correlations between changes of geometricalparameters and t...

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