background bipolar disorder is a biological brain disorder which is associated with debilitating fluctuation in mood and adverse effects on patients, their families and society. the importance of genetics and its role in bipolar disorder is a controversial issue to discuss. evidence indicates a relation between the risk of bipolar disorder and specific genes. amongst the genes whose role has be...

objective: this study evaluated the theory of mind (tom) in adolescents diagnosed with bipolar disorder ‎‎(bd) during their euthymic period compared to a typically developing (td) group.‎ method: the bd group consisted of thirty 11-18 year old inpatients in euthymic phase. the td ‎group included 30 age, gender, and iq matched volunteer students. to assess the diagnosis and ‎comorbid disorders, ...

objective: given that the topic of bipolar disorder overdiagnosis has been relatively neglected in the literature and considering its significance in psychiatric training. the present study was conducted through an objective structured clinical examination (osce) on psychiatric residents to assess the validity of their clinical diagnosis. methods: twenty forth residents participated in the exam...

the pathogenesis of bipolar i disorder (bp-i) involves immune-mediated mechanisms, especially an imbalance in pro-inflammatory/anti-inflammatory cytokines in plasma or cerebrospinal fluid. interleukin-1 (il-1) gene cluster, coding some of these pro-inflammatory cytokines, might play a role in various neuropathologies related to neuron inflammation. the aim of the present study was to investigat...

the aim of this study was to compare the level of anxiety and depression in patients admitted to surgery or internal departments. the study was carried out on 359 hospitalized patients over the age of 18 years and designed as a cross sectional survey. participants were recruited from internal medicine and surgery departments of khatam al anbia hospital, tehran, iran. information was collected u...

objective: bipolar disorder (bd) is a disabling psychiatric disorder with frequent recurrences. besides pharmacotherapy, psychoeducation could be helpful in reducing symptoms as well as recurrence of this disorder, leading to improvement of patients’ quality of life. this study aimed at investigating the effectiveness of a culturally adjusted structured program for training iranian bd patients....

Objectives: Psychiatric stigma refers to systemic and internalized stereotypical negative attitudes against individual with mental illness. This article describes the level of self stigma, stereotype endorsement and perceived discrimination experienced by patients with Bipolar-I disorder in Tehran. Methods: Data were collected from a total of 126 patients with Bipolar-I disorder who responde...

The aim of study was to evaluate the reliability of Persian form of quality of life questionnaire -36 Items in the patients with bipolar I disorder. Present study was cross sectional-descriptive. 50 patients with bipolar I disorder were selected from Mehregan hospital by convenient sampling. They were assessed with using of Persian form of quality of life questionnaire-36 items. 20 patients (40...

background: bipolar mood disorder type 1 is one of the most serious psychiatric disorders. we aimed to assess the efficacy of a short-term family–focused treatment for patients with bipolar mood disorder type 1 in a one-year follow-up period.   methods: sixty patients with bipolar mood disorder and acute mania episodes who referred to ibn-e-sina psychiatric hospital in mashhad were recruited. h...