Introduction: Gail model is one of the most important models for the evaluation of breast cancer risk between US white females. According to genetic diversity, there is a possibility of affecting the efficiency of the Gail model in risk assessment of breast cancer among Iranian populations. In this study, the Gail model efficiency in specifying the risk of breast cancer in Iranian population wa...

background prostate cancer is a serious genetic disease known as the first widespread cancer in men, yet the molecular changes required for the cancer progression is not fully understood. availability of high-throughput gene expression data has led to the development of various computational methods for the identification of critical genes involved in the cancer. methods in this paper, we show ...

Background: Thyroid cancer is the most common endocrine malignancy. Several risk factors were found to play a role in thyroid cancer. The purpose of the study was to determine the risk factors for thyroid cancer, in Babol, north of Iran. Method: 80 patients with thyroid cancer were selected as case group and 160 people living in the neighborhood of the patients as control group. Risk factors in...

results in this study, 57.8% males and 42.2% females participated, while the mean age of the patients was 68.46 years old, and the mean age of the healthy individuals was 59.79 years old. the findings of this study showed a family history of cancer, anemia, and smoking, and associations with education, occupation, socioeconomic status, blood group, consumption of hot drinks, as well as a histor...

background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

background: the area of contaminated lands exposed to the health risk of environmental pollutants is a matter of argument. in this study, a new method was developed to estimate the amount of area that is exposed to higher than normal levels of cr, mn, and v. methods: overall, 170 soil samples were collected from the upper 10 cm of soil in an arid area in central part of iran in semnan province....

abstract breast cancer is a multifactorial disease. benign breast disease (bbd) is one of the most important risk factors for breast cancer. the etiology of bbd is unknown. it is divided into nonproliferative and proliferative diseases. the selection of studies will be based on titles, abstract screening, inclusion and exclusion criteria, and quality assessment. previous studies have shown that...

background: in northeastern iran there is an area of high incidence of esophageal cancer which is populated by residents of turkmen ancestry. several environmental risk factors for esophageal cancer have been proposed, but the roles of familial and genetic factors have not been studied extensively in the turkmen population. materials and methods: we evaluated the importance of familial risk fac...

background the incidence and mortality rates of breast cancer are high among filipino women. the lack of knowledge on preventive behavior and early detection related to breast cancer is considered a reason. conclusions women who were aware of risk factors for breast cancer possessed a higher education level and had knowledge of the association of risk factors with preventive behaviors and early...