نتایج جستجو برای: cancers geroprotective
تعداد نتایج: 91117 فیلتر نتایج به سال:
Effects of long-term application of novel polyphenolic composition BP-C3, containing polyphenolic benzenepolycarboxylic acids, vitamins and minerals on some biomarkers of aging, life span and spontaneous tumorigenesis has been studied in female SHR mice. Administration of BP-C3 with drinking water (0.005%) did not exert any toxic effect (did not have effect on general condition of animals, weig...
background: in view of high prevalence of gi cancers in lorestan province, western iran, and a large number of esophageal cancer patients in this region, this study was done to determine the frequency of various gi cancers in the area. â methods: in a cross-sectional study, all patients from lorestan province for whom endoscoppy and colonoscopy were performed and biopsy was provided entered ou...
The modulation of longevity genes and aging-associated signaling pathways using pharmacological agents is one of the potential ways to prolong the lifespan and increase the vitality of an organism. Phytochemicals flavonoids and non-steroidal anti-inflammatory drugs have a large potential as geroprotectors. The goal of the present study was to investigate the effects of long-term and short-term ...
The major challenges of aging research include absence of the comprehensive set of aging biomarkers, the time it takes to evaluate the effects of various interventions on longevity in humans and the difficulty extrapolating the results from model organisms to humans. To address these challenges we propose the in silico method for screening and ranking the possible geroprotectors followed by the...
Abstract. Determining the biological age of human arteries is relevant for timely stratification risk developing diseases, prevention, control individual ageing rate, and geroprotective therapy. To study age-related changes in echocardiographic examination to develop a formula estimating arteries. Echocardiographic examinations heart were performed on 188 practically healthy people aged 30 79 y...
Background: Common cancers such as colon, breast, and lung cancer are increasing in developing countries. Objective: This study was conducted to determine 10-year trends and changes in common cancers in patients from a referral hospital in Tehran, Iran. Methods: This cross-sectional study investigated a study population comprising colon, stom...
Background and purpose: Introduction of antiretroviral therapy has led to decline in AIDS-associated cancers. In recent years, the rate of non-AIDS associated cancers has increased. Current prevalence of AIDS-associated cancers in Iran is unknown, so we aimed to investigate the prevalence of different cancers among HIV-infected patients in Iran. Materials and methods: A cross-sectional surv...
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