Candida species are the fourth most frequent cause of nosocomial bloodstream infections, and 25%-50% occur in critical care units. During an 18-month prospective study period, all patients admitted for > or = 72 hours to the surgical (SICUs) or neonatal intensive care units (NICUs) at each of the participant institutions were followed daily. Among 4,276 patients admitted to the seven SICUs in s...

BACKGROUND Denture stomatitis is a common oral lesion following the use of ill-fitting dentures. A layer of tissue conditioner is usually used to improve adaptation of the denture. These liners can support the in vivo adhesion and colonization of the oral Candida. The aim of this study was to evaluate the efficacy of the two common antifungal agents mixed with tissue conditioner against Candida...

The incidence of candidemia in the overall population ranges from 1.7 to 10 episodes per 100,000 inhabitants and Candida is one of the ten leading causes of bloodstream infections in developed countries. An estimated 33-55% of all episodes of candidemia occur in intensive care units (ICU) and are associated with mortality rates ranging from 5% to 71%. Candida fungemia may have an endogenous or ...

Candida albicans is a commensal yeast that is normally present in the oral cavity of the population. This opportunistic pathogen is frequently isolated from the human mouth but its presence in the oral cavity is not indicative of disease. Colonization of the oral cavity by Candida albicans involves the acquisition and maintenance of a stable yeast population. Micro-organisms are continually bei...

AIM The aim of this study was to assess and compare the quantitative and qualitative oral colonization of Candida species between a group of healthy tobacco smokers and a comparable group of nonsmokers, and to investigate a possible correlation between oral candidal colonization and the quantity or duration of the smoking habit. METHODS AND MATERIALS Fifty smokers and 50 nonsmokers were inclu...

Male ICR Swiss mice (2 to 3 months old) were fed Candida albicans in their drinking water for 3 days, followed by no treatment, antibiotics in their drinking water (daily), or immunosuppressants given by intraperitoneal injection (two to three times weekly) over a 3- to 4-week period. The organs of animals were processed to determine the numbers of C. albicans and total aerobic bacteria per g o...

Critical Care Medicine www.ccmjournal.org 565 C andida is the third most common agent responsible for healthcare-associated bloodstream infections and is the most common agent responsible for invasive fungal infections in children (1, 2). Candidemia is associated with a high mortality and morbidity among hospitalized patients as well as high healthcare costs (3). Prevalence of candidemia has dr...

UNLABELLED The colonization of the oral cavity is a prerequisite to the development of oropharyngeal candidiasis. AIMS The aims of this study were: to evaluate colonization and quantify Candida spp. in the oral cavity; to determine the predisposing factors for colonization; and to correlate the levels of CD4+ cells and viral load with the yeast count of colony forming units per milliliter (CF...

background and purpose: diabetic patients are more susceptible to oral candidiasis infection than non-diabetics due to the factors promoting oral carriage of candida. several factors can increase colonization of candida species in the oral cavity such as xerostomia, which reduces the salivary flow and is a salivary ph disorder. in the current study, we aimed to identify and compare the coloniza...