BACKGROUND The importance of human immunodeficiency virus (HIV) blip magnitude on virologic rebound has been raised in clinical guidelines relating to viral load assays. METHODS Antiretroviral-naive individuals initiating combination antiretroviral therapy (cART) after 1 January 2000 and achieving virologic suppression were studied. Negative binomial models were used to identify blip correlat...

Undirected graphical models encode in a graph G the dependency structure of a random vector Y . In many applications, it is of interest to model Y given another random vector X as input. We refer to the problem of estimating the graph G(x) of Y conditioned on X = x as “graph-valued regression”. In this paper, we propose a semiparametric method for estimating G(x) that builds a tree on the X spa...

Cocaine- and amphetamine-regulated transcript (CART) was originally isolated from rat brain, but CART is also synthesized and stored in the anterior pituitary. The localization of pituitary CART and factors regulating its synthesis are largely unknown. The regulation of pituitary CART synthesis and release in response to CRH and glucocorticoids was examined in vitro and in vivo. CART immunoreac...

This paper investigates consumers' response to conditional promotions (CP) offered in an offline retail store. Using qualitative research inquiry, we decipher the consumer decision-making process by finding linkages between 'pre-cart' and 'post-cart' add-on purchases. Thematic analysis of data (focus groups personal interviews) resulted four themes, i.e. 'Criticality Product Utility,' 'Mode Pay...

CART (cocaine- and amphetamine-regulated transcript) peptides are novel brain neuropeptides that have been shown to have a role in the control of feeding behavior in mammals. The effects of intracereboventricular (i.c.v.) administration of two CART fragments, CART (62-76) and CART (55-102) on feeding and behavioral activity of goldfish (Carassius auratus) were examined. Both CART peptide fragme...

Swinging up an inverted pendulum is a common benchmark task for the investigation of automatic control techniques. In this paper we introduce a new Fuzzy Sliding Mode (FSM) technique for swinging-up an inverted pendulum and controlling the connected cart, while minimizing the swing-up time, the cart travel and the required control action. The FSM technique adopted is based on a piecewise linear...

This paper explains the development of a newconcept three-wheeled electric cart that not only is a means of transportation, but also provides the driver with a way of getting some physical exercise. Based on an investigation of the physiological decline accompanying aging, pedaling was chosen to implement the function of maintaining or improving physical strength; and an ergonomically designed ...

BACKGROUND Other forms of tobacco use are increasing in prevalence, yet most tobacco control efforts are aimed at cigarettes. In light of this, it is important to identify individuals who are using both cigarettes and alternative tobacco products (ATPs). Most previous studies have used regression models. We conducted a traditional logistic regression model and a classification and regression tr...

We propose a new mechanism for implementing the electronic shopping cart system (shortly, the shopping cart system) on the World Wide Web system (the Web system). The electronic shopping cart system is one of typical clientserver systems, and it includes essential tasks to be implemented in the typical Web based client-server system. The most important task is to maintain context data between s...