Noting a negative correlation between average radon levels and lung cancer mortality in Montana counties, Hart (2011) “questions the notion that radon is deadly in Montana.” Results from a much larger ecological study of the correlation between county radon levels and lung cancer mortality across the whole United States were published in the 1990s (Cohen 1990, 1995). Like Hart, Cohen found an i...

We reviewed 27 published studies examining a possible association between sensory (visual or hearing) impairment and late-life psychosis with paranoid features. A majority of these investigations supported the postulated association between hearing impairment and late-onset schizophrenia or paranoid disorder. Many of the published studies, however, had important methodological limitations. In a...

Cancer colorectal : le rôle controversé Université de Toulouse, Aliments & Cancer de la consommation de viande INRA ENVT, 23 Capelles, 31076 Toulouse, France. Texte remis le 12 février 1997, accepté après révision le 9 juin 1997. Tirés à part: D.E. Corpet Summary : Diet is supposed to influence the colorectal cancer etiology, but the precise causative factors are yet unknown. International ecol...

Background: Cholecystitis is one of the major digestive diseases. Its prevalence is particularly high in some populations. Significant risk factors associated with cholecystitis include age, sex, obesity, diet, parity and type 2 diabetes. Objective: To determine the association between HLA-DRB1 and cholecystitis. Methods: This casecontrol study included forty Iraqi Arab patients who had cholecy...

The investigation of the role of nutrition in cancer etiology and the perception of its importance among concerned scientists has gone through various phases over the past 20 years, ranging from the enthusiasm of Candide, Voltaire's hero (we are in the best possible world and we know everything) to Hume's kind of skepticism (the subject is appealing but causality can never be shown). These ups ...

Causal Inference for Case-Control Studies by Sherri Rose Doctor of Philosophy in Biostatistics University of California, Berkeley Professor Mark van der Laan, Chair Case-control study designs are frequently used in public health and medical research to assess potential risk factors for disease. These study designs are particularly attractive to investigators researching rare diseases, as they a...

PURPOSE Lymphotoxin-Alpha (LTA) is a mediator of inflammation which may be associated with the risk of ischemic stroke (IS). Polymorphisms (-252A/G and -804C/A) in the LTA gene have been found to be associated with IS with contradictory results. The present meta-analysis aimed to provide a comprehensive account of the association of (-252A/G and -804C/A) gene polymorphisms of LTA gene with susc...