Reaction of trimethylaluminium with the linked bis(phenol) trans-1,4-dithiocyclohexanediyl-2,2-bis(4,6-di-tert-butylphenol) (cydtbpH2, 1a) led to the chiral methyl aluminium complex [Al(cydtbp)Me] (2a) as both racemate and resolved enantiomers, which were characterized by multinuclear NMR spectroscopy and elemental analysis. Rac-{trans-1,2-dithiocyclohexanediyl-2,2-bis(6-tert-butyl-4-methylphen...

1-Bromopinacolone, BrPin, acts initially as a reversible competitive inhibitor for acetylcholinesterase, KI = 0.18 mM in hydrolysis of acetylcholine. Unlike bromoacetone, with time it acts as an irreversible covalent inhibitor. BrPin has a hydrolytic half-life of 30 h at the pH of incubation, 7.8. The enzyme-BrPin complex is 50% inactivated in 2 h. First order kinetics are observed; the rate co...

In this paper, synthesis and antimicrobial properties of cationic dye were investigated. 4-acetylamino-N-2-aminomethylpyridine-1,8-naphthalimide was reacted with 1-bromobutane as the alkylating agent and a cationic dye was obtained. The final product was purified by column chromatography method. The chemical structure of the novel cationic dye and its intermediates was chracterisized by using F...

a novel quaternary ammonium-based cationic gemini surfactant (s6) having 1,6 di-bromo hexane as a spacer, have been used and its interaction with insulin in aqueous solution (ph, 7.40) was investigated by several methods including fluorescence spectroscopy, uv-vis spectroscopy, circular dichroism, dynamic light scattering, ζ-potential measurements, conductivity and transmission electron microsc...