aim: aquaporin4 (aqp4) is the main water channel in the brain that has important role in water transport across blood- brain- barrier. it has been proved that intracranial pressure and also expression of aqp4 increase in some disorders such as hydrocephalus, hyponatremia, cytotoxic oedema and brain tumours and drugs that can decrease the expression of this aqp can offer some treatment for these...

background: it is well known that the hippocampus, the ca1 pyramidal cells in particular, is selectively vulnerable during global cerebral ischemia. recently, it is observed that pentoxifylline has a neuroprotective effect. this study explored the pharmacological relationship between ischemia-induced cell death of the hippocampus and the efficacy of a vasodilator agent (pentoxifylline) in the p...

objective spastic cerebral palsy (cp) is one of the most difficult and disabling conditions that requires medical attention and treatment. the aim of this study was to assess the efficacy and safety of oral tizanidine in treating spasticity in children with spastic cp. materials & methods sixty children with spastic cerebral palsy were enrolled in a double-blind, placebo-controlled, randomized ...

introduction: cerebral palsy (cp) is anon-progressive abnormality of the developing brain that requires extensive and long-term rehabilitation. accordingly, people with cp may gainextensive experience of rehabilitation throughout their lives. understandingthese experiences wouldimprove the attitudes of rehabilitation service providers toward this group of patients. materials and methods: google...

Objectives: Cerebral palsy is the most common type of permanent movement and posture disorder in children leading to activity limitations. Childrenchr('39')s participation is influenced by their functional ability, skills, interests, and environmental factors. The objective of the study was to describe parent perception of environmental barriers to participation of children with cerebral palsy....

Objectives: The high number of cerebral palsy, the severe disability of this disorder, depression in disabilities, and long lasting effects of the child`s disability on the family especially mothers are the common issues. The purpose of this study was investigating the level of depression in mothers with cerebral palsy children and its related factors. Methods: This caused comparative study ...

thromboembolic phenomena are the serious consequences of assisted reproductive technology. we present a case of cerebral sinus vein thrombosis (cvst) following ovarian hyper stimulation syndrome (ohss). ten days after recovering from ohss, the patient presented in the emergency department with thunderclap headache. her magnetic resonance venography (mrv) showed occluded left transverse sinus an...

numerous etiologies are responsible for cases of stroke in young adults. this study reviews the causes of two types of stroke (ischemic and intracerebral hemorrhage) in young adults aged 15 to 40years, admitted to our center (a tertiary care center) from 1997 to 2002. the purpose of this study is to determine the relative frequency of causes of stroke in young adults and compare this with publi...

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cerebrovascular disease is one of the leading causes of death in the world, and about one-fourth of cerebrovascular deaths are due to ruptured cerebral aneurysms (ca). hence it is important to find a way to reduce aneurysm formation and its subsequent morbidity and mortality. proteolytic activity capable of lysing gelatin has been shown to be increased in aneurysm tissue and expression of plasm...