objectives: patients with hepatitis c virus infection are at high risk of getting hepatitis a virus. hepatitis a virus is an important widespread virus that usually causes more severe medical consequences in patients with chronic liver disease. the purpose of this study was to evaluate prevalence of hepatitis a virus antibody in patients with chronic hcv in isfahan province, iran. methods: a cr...

results the mean age of chb patients was 38.5± 11.9 years and 55.9% of them (231 patients) were male. there were 13 cases (3.1%) with hdv infection. there was no association between positive anti-hdv serology and factors such as age, gender, carrier state, liver enzymes, and positive hepatitis b e antigen (hbeag) serology. conclusions although hdv had a low prevalence in our area, it is importa...

By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. T...

BACKGROUND & OBJECTIVE The recent discovery of a novel parenterally transmitted, unenveloped, single-stranded DNA virus called TT virus (TTV) in chronic hepatitis patients with unclear pathogenesis throughout the world led us to investigate, its presence in chronic hepatitis patients attending a hospital in New Delhi, India, and to evaluate its role in liver disease. METHODS TT virus DNA was ...

hepatitis b virus (hbv) is the most prevalent viral infection and is among the leading causes of human liver diseases. nearly 360 millions of people are world widely infected with prolonged forms of hepatitis b including active and inactive chronic forms. chronic hepatitis b (chb) is associated with cirrhosis and hepatocellular carcinoma (hcc) in patients suffering from congenital and/or acquir...

conclusions this study indicates that the rate of g1896a mutation at the pc region among hbeag negative patients, in the golestan province of iran, was similar to the average rate encountered in other parts of iran. the pc stop codon mutation was detected in 93.18% of hbeag negative patients. further studies with larger sample sizes are required to elucidate the exact role of these mutations in...

With up to 400 million affected people worldwide, chronic hepatitis B virus (HBV) infection is still a major health care problem. During the last decade, several novel therapeutic approaches have been developed and evaluated. In most regions of the world, interferon-α (IFN-α), and nucleos(t)ide analogues are currently approved. Despite major improvements, none of the existing therapies is optim...

Background and Aims: Torque teno virus (TTV) is a DNA virus that isolated from the serum of a Japanese patient without A-G transfusion-transmitted hepatitis and other etiology. TTV is detectable in plasma and peripheral blood mononuclear cells, different body fluids and secretions such as stools, saliva, semen, vaginal fluid. The genome exhibits high diversity that has enabled the determination...

hepatitis b virus infection is a major public health problem worldwide. islamic republic of iran is a country in which hepatitisb prevalence is intermediate. the aim of this study is to assess prevalence of chronic hepatitis b infection in iran according to demographic characteristics. all cross-sectional studies concerning  revalence of chronic hepatitis b infection in iran were included irres...