background immune cells and molecules play a vital role in initiating, maintaining, and regulating immunological homeostasis and inflammation in many pathological and physiological processes; however, the changes on expressions and functions of these cells and molecules in hepatitis b virus (hbv) infection has not been elucidated well. conclusions cxcr3-associated chemokines might contribute to...

Background: Blood transfusion plays a great role in public health and the blood safety still has remained a main concern. HBV has been considered as one of the most prevalent blood borne infections. It is estimated that chronic HBV affects 350-400 million people worldwide. Comprehensive knowledge about HBV has high importance in Iran due to high number of blood dependent patients. Material ...

Endocarditis and intracardiac infection have been increased recently especially in dialysis dependent renal failure patients. This is usually intractable infection to broad spectrum Antibiotic therapy and in most cases surgical intervention was necessary. We have presented 45 years old man with intracardiac infection at the tip of dialysis catheter that after catheter removal intracardiac infec...

autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. hepatitis c virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis c virus infection and some autoimmune disease has been st...

conclusions serum stnfr-iiα could be used as a potential serum marker in diagnosing hcc among patients with hcv infection. results the serum level of stnfr-iiα was significantly higher in patients with hcc in comparison to the other groups. a positive correlation was found between the serum levels of stnfr-iiα and ast and alt in patients of group-ii. diagnosis of hcc among patients with hcv inf...

results the frequencies of the aa, at, and tt genotypes were 31%, 51%, and 18% in the chronic hbv patient group, and 40%, 45%, and 15% in the healthy control group, respectively. however, a lack of association of the + 874 polymorphism in the ifn-γ gene of those with chronic hbv infection was found. evaluation of hbv association with this polymorphism was significant under the dominant genetic ...

hepatitis delta virus (hdv) infection results in more severe and even fulminant form of hepatitis b in co-infected cases. this study was designed to estimate the prevalence of anti-hdv positivity and the associated risk factors in patients with chronic hepatitis b virus infection in zahedan (iran). in this cross-sectional study a total of 440 consecutive patients with chronic hepatitis b virus ...

conclusions the mir-155 appeared to be suppressed during hbv infection. the significantly higher mir-155 levels in alt-elevated patients infected with hbv suggest that mir-155 levels in pbmcs correlate with the immune state of patients with chronic hbv infection. results in the hbv-infected patients, the mir-155 levels were significantly lower than in the healthy controls (p = 0.001). chronic h...