Introduction Venous thrombosis is the leading cause of pregnancy-related maternal morbidity and mortality. The risk increased by caesarean section blood loss, though underlying mechanisms these prothrombotic changes remain unknown. Materials methods This prospective study recruited 50 pregnant women at term undergoing elective University Hospital Magdeburg, Germany. Blood loss during surgery wa...

The field of coagulation testing has undergone some major technological and conceptual developments, which are briefly reviewed here. The assessment of coagulation parameters is no longer restricted to the study of clot formation and its dissolution. The understanding of the biochemical nature of coagulation processes, coupled with the development of new therapeutic agents in the treatment of h...

BACKGROUND Third-generation hydroxyethyl starch (HES) solutions have been developed to minimize negative effects on hemostasis. In normal pregnancy, the coagulation activity increases, reaching a maximum around term. This study examined the effects of hemodilution with HES 130/0.4 (6%) on blood coagulation in parturients in vivo and in vitro. METHODS Forty parturients scheduled for cesarean s...

introduction: the main inhibitors of coagulation pathway are antithrombin (at), protein c and protein s. these inhibitors are necessary to prevent thromboembolism. hereditary deficiency of inhibitors is the main cause of alteration in balance between the anti-clotting and the formation of thrombin. patients with this abnormality are susceptible to venous thromboembolism (vte). two major clinica...

background some of the dental procedures can cause bleeding. bleeding control can be difficult in some patients because of systemic disease or chronic anticoagulant therapy, so they may be at increased risk for bleeding occurrences or even death following invasive dental procedures. this study was schemed to measure the knowledge of general dentists in shiraz city regarding coagulation tests pe...

Factor X deficiency is the most common coagulation factor deficiency amongst patients with AL amyloidosis. It presumably occurs due to adsorption of factor X to amyloid fibrils. The deficiency of this factor, in conjunction with other hemostatic defects, can cause bleeding complications. A case of acquired factor X deficiency due to AL amyloidosis is reported, where abnormal coagulation paramet...

Effects of repeated administration ofphenobarbital (PB) on blood coagulation-related parameters were examined in non-pregnant, pregnant and lactating rats, and also in pups born to PB-treated lactating dams. PB was orally administered at a dose level of 80 mglkglday to pregnant (from gestation day (GD) 13), postpartum (from postpartum day (PPD) 7) and non-pregnant rats (from 13 weeks of age) fo...

The effects of repeated administration of phenobarbital (PB) on blood coagulation time were examined using male Japanese white SPF rabbits, which are widely used for toxicological studies. PB was administered to the rabbits by oral gavage for 2 weeks, at dose levels of 0, 12.5, 25 and 50 mg/kg/day. Blood was collected on Days 8 and 14 after each day's dosing to perform blood coagulation examina...

position of abomasum is positioned below the rumen in the right of the ventral midline. Left displacement of abomasum (LDA) is a condition in which abomasum is trapped between the rumen and left abdominal wall. LDA occurs most commonly in large, high-producing adult dairy cows after parturition (1). Many papers have been described risk factors, pathogenesis, diagnosis, treatment and outcome of ...